A newer drug called denosumab (Xgeva™, Prolia™) is also now available to help reduce the risk of problems from breast cancer metastasis to the bone. It works in a different way from bisphosphonates.
In studies of patients with breast cancer that had spread to the bone, it seemed to help prevent problems like fractures (breaks). It also can help bones even after bisphosphonates stop working. It can also be used to help keep bones strong in women on aromatase inhibitors.
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