Many of the breakdown products of chemotherapy drugs are excreted through the kidneys. These drug by-products can damage the kidneys, ureters, and bladder. If you have a history of kidney problems, you may be at a higher risk for kidney damage.
Certain chemotherapy drugs such as cisplatin, cyclophosphamide, high-dose methotrexate, ifosfamide, and streptozocin are more likely to cause kidney and urinary damage than others.
Signs of possible kidney problems:
- Headache
- Pain in the lower back
- Fatigue
- Weakness
- Nausea
- Vomiting
- High blood pressure
- Faster breathing rate
- Change in how often you urinate
- Change in color of urine
- Swelling or puffiness of the body
Blood tests to measure kidney function are done regularly to watch for any changes.
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