Dr. Len's Cancer Blog

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Dr. Len's Cancer Blog

The American Cancer Society

Lung-MAP--A Bold Initiative To Find New Treatments For Squamous Cell Lung Cancer--Launches Today

by Dr. Len June 15, 2014

Today marks a major step forward in cancer clinical trials and drug development with the launch of the Lung-MAP protocol to evaluate new treatments for squamous cell lung cancer, a common cancer which has proven resistant to the standard drugs currently available. In response to this genuine unmet need, Lung-MAP has been designed to move new therapies more quickly from the laboratory to the bedside of patients afflicted with this serious disease and few options available.

Many--including present company--have written about the need to improve this process. We are in a new era of cancer drug development, spearheaded by our ever increasing knowledge of cancer genes and the targets within those genes that can be used to disrupt the cancer cell on its inexorable road to proliferation and destruction. Getting those drugs speedily through development and clinical testing has been a real challenge. And, going forward, finding the patients with the "right" genomic signature who are candidates to receive these therapies is going to be difficult. In simple terms, we need to find the patients where they live and match them to these new drugs as quickly as possible. And that hopefully will translate into more and better treatments for patients, and save lives. More...

ASCO 2014 Is A Wrap: If Immunotherapy Is The Queen Of The Ball, Then Panomics Holds The Keys To The Kingdom

by Dr. Len June 04, 2014

As in years past, the trip home from the Annual Meeting of the American Society of Clinical Oncology in Chicago gives me a moment to reflect on what I have heard and hopefully learned over the past five days.

This meeting is a whirlwind of activity and information, far too much for any one person to absorb and process. You can be focused on one topic, you can be general, and you can hear new cutting edge research or be educated on topics of general interest in cancer. You can go to the exhibit hall and be overwhelmed by the booths and displays (I tend not to go there, but obviously many others do). I suspect you get the idea.

Ultimately for me it is the take away messages about trends in cancer research and cancer care that matter the most personally. And this year the trends appear to be somewhat similar to past years, with perhaps some new wrinkles. What is undeniable is that if immunotherapy is the queen at the ball, then "panomics" (I really like that word) holds the keys to the kingdom. More...

The Picture With The Smile That Says So Much About Advances In Cancer Care

by Dr. Len June 04, 2014

It was the picture (see below) that, to me, said it all: a 96 year old woman -- one of the first patients in the world to receive a brand new cancer drug--, and a large tumor on her neck had melted completely away. But it was the smile on her lips that you couldn't avoid noticing. More...

Big Steps Forward In Melanoma Treatment But Tread Carefully

by Dr. Len June 02, 2014

The brave new world of melanoma treatment continues at the Annual Meeting of the American Society of Clinical Oncology in Chicago. And notwithstanding the excitement, there are some other pieces of information around the edges that remind us once again that a breakthrough today may not be quite as promising when viewed a couple of years from now. More...

In An Era Of Bold New Cancer Treatments An Older Drug Shows Real Promise For Advanced Prostate Cancer

by Dr. Len June 02, 2014

The annual meeting of the American Society of Clinical Oncology here in Chicago is a place where many commercial interests jostle for attention to make their latest promising therapy the star of the show. But this weekend, a standard widely available generic drug stole the show by producing incredible results in improving survival for men with advanced prostate cancer. And that has some of us asking, "Why did it take so long to find out? More...

From The ASCO Meeting In Chicago: A Focus On Cost, Value, And Financial Toxicity Of Cancer Care

by Dr. Len May 31, 2014

At the annual meeting of the American Society of Clinical Oncology (ASCO) here in Chicago, something vitally important is happening: there is an increasing recognition of something no one really wanted to talk about in polite company until now. It is the fact that the costs of many of the new treatments being developed are extraordinary.

The headlines about cost and value of cancer care greeted me when I walked into the McCormick Center in Chicago for the opening sessions of the meeting. This is the leading cancer meeting in the world, and what happens here makes news worldwide, significantly impacting the lives of patients with cancer wherever they may be.

Now there is an increasing recognition of the elephant in the room: the costs of these new treatments are extraordinary. No matter how one chooses to slice and dice the arguments, these drugs are expensive with costs per month of $8000 and upwards getting a lot of attention and increasing concerns, especially at this meeting. More...

The FDA Lays Down The Law About The Dangers Of Indoor Tanning

by Dr. Len May 29, 2014

In what has to be considered a major victory for those concerned about the proliferating use and risks of tanning beds, the Food and Drug Administration this week issued a final rule requiring devices used for indoor tanning to meet very specific requirements before they can be marketed to the public. And in what is probably an even more important part of the rule, they now instruct those who market tanning devices to consumers to warn them clearly about the very real and serious risks of indoor tanning. More...

"Don't Fry Day" Reminds Us To Take Care Of Our Skin Since It's The Only One We Get

by Dr. Len May 22, 2014

"Don't Fry Day," which we "celebrate" every year on the Friday before Memorial Day is an annual reminder to be good to the skin you're in. It's the only one you get. Wear it out or damage it and you don't get to replace it, like we do with heart valves, knees, hips, and so on.

This year Don't Fry Day is even more personal to me. After hounding all of you to be careful in the sun, I got a very personal reminder this past year of why that's important: two surgeries and two scars from removing skin cancers. One of those scars is pretty visible and a daily reminder of my own past unwise sun behavior. Like many folks, I'm glad the cancer is gone. But I also wish it hadn't been there in the first place.

The reality is that my generation had very little knowledge and very few options when it came to avoiding the dangers of too much sun exposure. We went outdoors, we went to the beach, we didn't have sunscreen, and we just lay there and took it. We thought we looked good. If we worked outdoors--like I did when I was in high school and college--we took our sunburn "lumps" early in the season then "built" a tan over the rest of the summer.

The rewards for our behavior? It certainly wasn't better health. We now have aging skin, with sunspots, wrinkles, and cancers to show for our efforts. And, unfortunately, we have also lost many friends, family, and others to serious skin cancers, such as melanoma. More...

We Need A Sense Of Urgency To Assure The Safety Of Health Information Technology

by Dr. Len May 16, 2014

This was the dream: we would use technology to create a seamless healthcare system, one where people, computers and machines would work together to improve patient care in many different ways. Health care would be more efficient, it would be safer, it would be less expensive, we would be able to transfer health-related information quickly and accurately.

After spending three days at a meeting this past week with some of the top experts in the field, I am not so certain that the dream is going to come true anytime soon. Perhaps more concerning, the problems--including patient safety issues--that are cropping up in so many areas are very troubling. More...

Relay For Life Is All About People Making A Difference In The Fight Against Cancer Every Day In So Many Ways

by Dr. Len May 11, 2014

My wife and I did something special this past Friday evening. We attended a Relay for Life in our hometown of Thomasville GA. And the memories of the event will not be soon forgotten, for so many reasons. More...

About Dr. Len

Dr. Len

J. Leonard Lichtenfeld, MD, MACP - Dr. Lichtenfeld is Deputy Chief Medical Officer for the national office of the American Cancer Society.

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