Castleman Disease

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References: Castleman disease detailed guide

Bowne WB, Lewis JJ, Fillipa DA, et al. The management of unicentric and multicentric Castleman disease. Cancer. 1999;85:706–717.

Chronowski GM, Ha CS, Wilder RB, et al. Treatment of unicentric and multicentric Castleman disease and the role of radiotherapy. Cancer. 2001;92:670–676.

Dispenzieri A, Armitage JO, Loe MJ, et al. The clinical spectrum of Castleman’s disease. Am J Hematol. 2012;87:997–1002.

Dispenzieri A, Gertz MA. Treatment of Castleman’s disease. Curr Treat Options Oncol. 2005;6:255–266.

Fajgenbaum DC, van Rhee F, Nabel CS. HHV-8-negative, idiopathic multicentric Castleman disease: Novel insights into biology, pathogenesis, and therapy. Blood. 2014 Mar 12. [Epub ahead of print]

Galeotti C, Tran TA, Franchi-Abella S, et al. IL-1RA agonist (anakinra) in the treatment of multifocal Castleman disease: Case report. J Pediatr Hematol Oncol. 2008;30:920–924.

Greiner TC, Gross TG. Atypical immune lymphoproliferations. In: Hematology: Basic Principles and Practice, 5th ed. Hoffman R, Benz Jr. E, Shattil SJ, Furie B, Silberstein LE, McGlave P, Heslop H, eds. Philadelphia, PA. Elsevier; 2009: 1449–1459.

Herrada J, Cabanillas F, Rice L, et al. The clinical behavior of localized and multicentric Castleman disease. Ann Intern Med. 1998;128: 657–662.

Kurzrock R, Voorhees PM, Casper C, et al. A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease. Clin Cancer Res. 2013;19:3659–3670.

Nagubandi R, Wang Y, Dutcher JP, Rao PM. Classic case of unicentric mixed-type Castleman’s disease. J Clin Oncol. 2013;31:e452–455

Nishimoto N, Kanakura Y, Aozasa K, et al. Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood. 2005;106:2627–2632.

Marcelin AG, Aaron L, Mateus C, et al. Rituximab therapy for HIV-associated Castleman disease. Blood. 2003;102:2786–2788.

Mylona EE, Baraboutis IG, Lekakis LJ, et al. Multicentric Castleman’s disease in HIV infection: A systematic review of the literature. AIDS Rev. 2008;10:25–35.

Powles T, Stebbing J, Bazeos A, et al. The role of immune suppression and HHV-8 in the increasing incidence of HIV-associated multicentric Castleman’s disease. Ann Oncol. 2009;20:775–779.

Talat N, Schulte KM. Castleman’s disease: Systematic analysis of 416 patients from the literature. Oncologist. 2011;16:1316–1324.


Last Medical Review: 07/07/2014
Last Revised: 07/07/2014