Castleman Disease

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Treating Castleman Disease TOPICS

Surgery for Castleman disease

Surgery is often used to obtain a tissue sample to diagnose Castleman disease (CD). A lymph node biopsy (described in “How is Castleman disease diagnosed?”) is usually a minor procedure, and patients can often go home afterwards.

Surgery also works well to treat localized (unicentric) CD. The type of surgery depends on where the disease is located.

If the involved lymph node or nodes are in a place that is easy to get to, such as in the armpit, then surgery is usually straightforward. In many cases the person may even be able to go home the same day after the surgery.

When the enlarged lymph nodes are in a place that is hard to get to, like deep in the chest or abdomen, surgery is more complex. The patient often has some pain and may need to stay in the hospital for a few days after the operation.

Aside from pain, possible side effects of surgery can include poor wound healing, bleeding at the surgery site, and infection. Depending on the site of surgery, other side effects are also possible.


Last Medical Review: 06/11/2012
Last Revised: 06/11/2012