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Survival Rates for Gastrointestinal Stromal Tumors

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Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed. They can’t tell you how long you will live, but they may help give you a better understanding of how likely it is that your treatment will be successful.

Keep in mind that survival rates are estimates and are often based on previous outcomes of large numbers of people who had a specific cancer, but they can’t predict what will happen in any particular person’s case. These statistics can be confusing and may lead you to have more questions. Ask your doctor how these numbers might apply to you.

What is a 5-year relative survival rate?

A relative survival rate compares people with the same type and stage of gastrointestinal stromal tumor (GIST) to people in the overall population. For example, if the 5-year relative survival rate for a specific stage of GIST is 90%, it means that people who have that cancer are, on average, about 90% as likely as people who don’t have that cancer to live for at least 5 years after being diagnosed.

Where do these numbers come from?

The American Cancer Society relies on information from the Surveillance, Epidemiology, and End Results (SEER) database, maintained by the National Cancer Institute (NCI), to provide survival statistics for different types of cancer.

The SEER database tracks 5-year relative survival rates for GIST in the United States, based on how far the cancer has spread. The SEER database, however, does not group cancers by AJCC TNM stages (stage 1, stage 2, stage 3, etc.). Instead, it groups cancers into localized, regional, and distant stages:

  • Localized: The cancer is limited to the organ where it started (for example, the small intestine, esophagus, or stomach).
  • Regional: The cancer has grown into nearby structures or spread to nearby lymph nodes.
  • Distant: The cancer has spread to distant parts of the body such as the liver.

5-year relative survival rates for GIST

These numbers are based on people diagnosed with GIST [small intestine, esophagus, colon, rectum, peritoneum, stomach, omentum] between 2012 and 2018.

SEER* Stage

5-Year Relative Survival Rate

Localized

95%

Regional

84%

Distant

52%

All SEER stages combined

85%

*SEER= Surveillance, Epidemiology, and End Results

Understanding the numbers

  • These numbers apply only to the stage of the cancer when it is first diagnosed. They do not apply later on if the cancer grows, spreads, or comes back after treatment.
  • These numbers don’t take everything into account. Survival rates are grouped based on how far the cancer has spread, but other factors, such as your age and overall health, whether the cancer can be resected (removed), and how well the cancer responds to treatment, can also affect your outlook.
  • People now being diagnosed with GIST may have a better outlook than these numbers show. Treatments have improved over time, and these numbers are based on people who were diagnosed and treated at least five years earlier.

The American Cancer Society medical and editorial content team

Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.

SEER*Explorer: An interactive website for SEER cancer statistics [Internet]. Surveillance Research Program, National Cancer Institute. Accessed at https://seer.cancer.gov/explorer/ on February 23, 2023.

Last Revised: March 1, 2023

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