Gestational Trophoblastic Disease

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What Is Gestational Trophoblastic Disease? TOPICS

What are the key statistics about gestational trophoblastic disease?

Gestational trophoblastic (jeh-STAY-shuh-nul troh-fuh-BLAS-tik) disease (GTD) occurs in about 1 pregnancy out of 1,000 in the United States. Most of these are hydatidiform (HY-duh-TIH-dih-form) moles.

Choriocarcinoma (KOR-ee-oh-KAR-sih-NOH-muh), a malignant form of gestational trophoblastic disease (GTD), is even less common, affecting around 2 to 7 of every 100,000 pregnancies in the United States.

Choriocarcinoma and other forms of GTD are more common in many Asian and African countries.

Overall, gestational trophoblastic tumors account for less than 1% of female reproductive system cancers.

Cure rates depend on the type of GTD and its stage, as described in the section “Treatment of gestational trophoblastic disease by type and stage.”


Last Medical Review: 02/06/2014
Last Revised: 03/03/2014