Gestational Trophoblastic Disease

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References: Gestational trophoblastic disease detailed guide

Alifrangis C, Agarwal R, Short D, Fisher RA, Sebire NJ, Harvey R, Savage PM, Seckl MJ. EMA/CO for high-risk gestational trophoblastic neoplasia: good outcomes with induction low-dose etoposide-cisplatin and genetic analysis. J Clin Oncol. 2013 Jan 10;31(2):280-6. Epub 2012 Dec 10.

Altieri A, Franceschi S, Ferlay J, et al. Epidemiology and aetiology of gestational trophoblastic diseases. Lancet Oncol. 2003;4:670-678.

American Joint Committee on Cancer. Gestational trophoblastic tumors. In: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer; 2010:437-444.

Berkowitz RS, Goldstein DP. Gestational trophoblastic diseases. In: Hoskins WJ, Perez CA, Young RC, Barakat RR, Markman M, Randall ME, eds. Principles and Practice of Gynecologic Oncology. 4th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2005:1055-1076.

Berkowitz RS, Goldstein DP. Current management of gestational trophoblastic diseases. Gynecol Oncol. 2009;112:654-662.

Berkowitz RS, Goldstein DP. Molar pregnancy. N Engl J Med. 2009; 360:1639-1645.

Diver E, May T, Vargas R, Bernstein M, Goldstein D, Berkowitz R. Changes in clinical presentation of postterm choriocarcinoma at the New England Trophoblastic Disease Center in recent years. Gynecol Oncol. 2013 Sep;130(3):483-6. Epub 2013 Jun 15.

El-Helw LM, Hancock BW. Treatment of metastatic gestational trophoblastic neoplasia. Lancet Oncol. 2007;8:715-724.

Fisher RA, Hodges MD, Newlands ES. Familial recurrent hydatidiform mole: a review. J Reprod Med. 2004;49:595-601.

Goldstein DP, Berkowitz RS. Gestational trophoblastic disease. In: Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, Kastan MB, McKenna WG, eds. Clinical Oncology. 4th ed. Philadelphia, Pa: Elsevier; 2008:1857-1874.

Goldstein DP, Berkowitz RS. Gestational trophoblastic neoplasms. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 9th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2011:1363-1367.

National Cancer Institute Physician Data Query (PDQ). Gestation Trophoblastic Tumors Treatment. 4/12/2013. Accessed at www.cancer.gov/cancertopics/pdq/treatment/gestationaltrophoblastic/HealthProfessional on October 9, 2013.

Osborne RJ, Filiaci V, Schink JC, et al. Phase III Trial of Weekly Methotrexate or Pulsed Dactinomycin for Low-Risk Gestational Trophoblastic Neoplasia: A Gynecologic Oncology Group Study. J Clin Oncol. 2011 Mar 1;29(7):825-31. Epub 2011 Jan 24.

Palomer JT, Feltmate CM. Choriocarcinoma. In: Schottenfeld D and Fraumeni JF, eds. Cancer Epidemiology and Prevention, 3rd ed. Oxford: Oxford University Press; 2006:1075-1086.

Seckl MJ, Sebire NJ, Berkowitz RS. Gestational trophoblastic disease. Lancet. 2010 Aug 28;376(9742):717-29. Epub 2010 Jul 29.

Shih IM. Gestational trophoblastic neoplasia--pathogenesis and potential therapeutic targets. Lancet Oncol. 2007:8:642-650.

Vencken PM, Ewing PC, Zweemer RP. Epithelioid trophoblastic tumour: a case report and review of the literature. J Clin Pathol. 2006 Dec;59(12):1307-8.

Yarandi F, Eftekhar Z, Shojaei H, et al. Pulse methotrexate versus pulse actinomycin D in the treatment of low-risk gestational trophoblastic neoplasia. Int J Gynaecol Obstet. 2008;103:33-37.


Last Medical Review: 02/06/2014
Last Revised: 03/03/2014