Treatment of children with juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is fairly rare, and there is no standard treatment for this leukemia. A stem cell transplant offers the best chance to cure JMML and is the treatment of choice when possible. About half of the children with JMML who get a stem cell transplant are still free of leukemia after several years. Sometimes, even if the leukemia recurs, a second stem cell transplant can be helpful. Because JMML is hard to treat with current chemo drugs, taking part in a clinical trial looking at newer drugs may be a good option for children who cannot get a stem cell transplant.