October 24, 2011
By Ted Gansler, MD, MBA, MPH
You have probably seen and heard a lot about breast cancer during the past few weeks, but as we approach the end of this year's breast cancer awareness month this is a good time to ask how much of the information you encountered is actually true. See if you know which of the following statements are true and which are false... More...
October 14, 2011
By William Chambers, PhD
Earlier this month, 3 immunologists were awarded the Nobel Prize for Medicine and Physiology. Two of the 3, Bruce Beutler and Ralph Steinman, are former research grantees of the American Cancer Society, bringing the total of Nobel Prize winners who are former grantees to 46. Drs. Beutler and Jules Hoffman, the third awardee, were singled out for their work on non-adaptive immunity, and Dr. Steinman was recognized for his discovery of dendritic cells, which are singularly important in adaptive immunity. So why is their work important, and what does it have to do with the fight against cancer? More...
October 05, 2011
EDITOR'S NOTE: This blog was originally published on June 29. Due to recent questions on this topic, it's been reposted. News reports say the United States Preventive Services Task Force will next week release new recommendations saying that healthy men should no longer receive a PSA blood test to screen for prostate cancer. Reports say the USPSTF will say the test does not save lives and often leads to more tests and treatments that needlessly cause pain, impotence and incontinence. Otis W. Brawley, M.D., chief medical officer of the American Cancer Society, says the Society cannot comment on the evidence review or on the recommendations until they are made public.
By Otis W. Brawley, MD, FACP
Prostate cancer is a major public health problem. The American Cancer Society estimates that 240,890 American men will be diagnosed with prostate cancer in 2011 and 33.720 will die of it. It is the second leading cause of cancer death among men, only surpassed by lung cancer.
Prostate cancer screening became common in the U.S. in the early 1990s and dramatically changed the demographic of cancer in the U.S. Prostate cancer quickly became the most commonly diagnosed non-skin cancer. Today an American male has a lifetime risk of prostate cancer diagnosis of about 1 in 6 and a lifetime risk of dying of only 1 in 36. In Western European countries where screening is not common, the lifetime risk of prostate cancer diagnosis is much lower, about 1 in 10, and the lifetime risk of death is the same.
Screening began without the completion of the scientific research to show that it saves lives. For most advocates of screening and aggressive treatment, there was and is a desire to do something that might be beneficial to the population of men at risk. Unfortunately, the history of medicine is filled with examples of physicians "jumping the gun" and using possible interventions before they are fully evaluated. More...