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The body is made up of hundreds of millions of living cells.
Normal body cells grow, divide, and die in an orderly fashion. During
the early years of a person's life, normal cells divide faster to allow
the person to grow. After the person becomes an adult, most cells
divide only to replace worn-out or dying cells or to repair injuries.
Cancer begins when cells in a part of the body start to grow
out of control. There are many kinds of cancer, but they all start
because of out-of-control growth of abnormal cells.
Cancer cell growth is different from normal cell growth.
Instead of dying, cancer cells continue to grow and form new, abnormal
cells. Cancer cells can also invade (grow into) other tissues,
something that normal cells cannot do. Growing out of control and
invading other tissues are what makes a cell a cancer cell.
Cells become cancer cells because of damage to DNA. DNA is in
every cell and directs all its actions. In a normal cell, when DNA gets
damaged the cell either repairs the damage or the cell dies. In cancer
cells, the damaged DNA is not repaired, but the cell doesn't die like
it should. Instead, this cell goes on making new cells that the body
does not need. These new cells will all have the same damaged DNA as
the first cell does.
People can inherit damaged DNA, but most DNA damage is caused
by mistakes that happen while the normal cell is reproducing or by
something in our environment. Sometimes the cause of the DNA damage is
something obvious, like cigarette smoking. But often no clear cause is
found.
In most cases the cancer cells form a tumor. Some cancers,
like leukemia, rarely form tumors. Instead, these cancer cells involve
the blood and blood-forming organs and circulate through other tissues
where they grow.
Cancer cells often travel to other parts of the body, where
they begin to grow and form new tumors that replace normal tissue. This
process is called metastasis.
It happens when the cancer cells get into the bloodstream or lymph
vessels of our body.
No matter where a cancer may spread, it is always named for
the place where it started. For example, breast cancer that has spread
to the liver is still called breast cancer, not liver cancer. Likewise,
prostate cancer that has spread to the bone is metastatic prostate
cancer, not bone cancer.
Different types of cancer can behave very differently. For
example, lung cancer and breast cancer are very different diseases.
They grow at different rates and respond to different treatments. That
is why people with cancer need treatment that is aimed at their
particular kind of cancer.
Not all tumors are cancerous. Tumors that aren't cancer are
called benign.
Benign tumors can cause problems -- they can grow very large
and press on healthy organs and tissues. But they cannot grow into
(invade) other tissues. Because they can't invade, they also can't
spread to other parts of the body (metastasize). These tumors are
almost never life threatening.
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