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Detailed Guide: Esophagus Cancer
Radiation Therapy

Radiation therapy uses high-energy radiation to kill cancer cells. External-beam radiation therapy focuses radiation from outside the body on the cancer. This type of radiation therapy is most often used to treat esophageal cancer. Internal radiation therapy, also known as brachytherapy, places radioactive material directly into or near the cancer.

Radiation therapy can be used as the primary (main) treatment of esophageal cancer in some patients. It is used more often for people who can't have surgery due to poor health. In fact, some doctors think radiation therapy can be as effective as surgery when it is combined with chemotherapy.

Radiation therapy may be given after surgery, to kill any tiny deposits of cancer cells that may have been left behind but are too small to see. This is known as adjuvant therapy. When radiation is be used to ease the symptoms of esophageal cancer such as pain, bleeding, difficulty swallowing it may be called palliative therapy.

Most often, radiation therapy is combined with surgery and/or chemotherapy. Use of radiation therapy combined with chemotherapy might be curative for some people and provide good relief of symptoms and extend survival for others.

The form of radiation therapy known as brachytherapy is useful in shrinking tumors so a patient can swallow more easily. In this procedure, radioactive seeds are placed into the tumor through an endoscope. This technique cannot be used to treat a very large area, so it is better used as a way to relieve symptoms (and not to cure the cancer).

Side effects of radiation therapy may include:

  • skin changes -- ranging from something like a sunburn to blistering and open sores
  • nausea and vomiting
  • diarrhea
  • fatigue
  • painful sores in the mouth and throat

These side effects are often worse if chemotherapy is given at the same time as radiation. During treatment of the esophagus, the radiation kills the normal cells in the lining, leading to painful swallowing. This improves after treatment. Most side effects of radiation are temporary, but some rare serious side effects can be permanent. For example, radiation to the chest can cause lung damage, which may lead to problems breathing and shortness of breath.

Talk with your doctor before and during treatment about what side effects you can expect and any ways that they may be reduced.

Last Medical Review: 05/04/2009
Last Revised: 05/13/2009

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