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How Cancer Treatment Affects Sexual Desire and Response

Lack of desire

Both men and women often lose interest in sex during cancer treatment, at least for a time. At first, concern for survival is so great that sex is far down on your list of needs. This is quite normal. Few people are interested in sex when they feel their lives are being threatened. When people are in treatment, loss of desire may result from worry, depression, nausea, pain, or fatigue.

Cancer treatments that disturb the normal hormone balance can also lessen sexual desire. If there is a conflict in the relationship, one partner or both might lose interest in sex. Any emotion or thought that keeps a woman from feeling excited can interfere with desire for sex. Distracting thoughts can keep her from getting aroused. Her vagina then stays tight and dry, which can make intercourse painful.

Many people who have cancer worry that a partner will be turned off by changes in their bodies or by the very word "cancer." These worries can affect desire.

Pain

Pain is a common problem for women during intercourse. It is often related to changes in the vagina's size or moistness. These changes can happen after pelvic surgery, radiation therapy, menopause, or treatment that has affected a woman's hormones.

Sometimes the pain sets off a problem called vaginismus. If a woman has vaginismus, the muscles around the opening of the vagina become tense without the woman being aware of it. Her partner cannot enter the vagina. Pushing harder increases the woman's pain because her vaginal muscles are clenched in a spasm. Vaginismus can be treated with counseling and some special relaxation training. These treatments are described in the section, "Ways of dealing with sexual problems."

Premature menopause

Another common way that cancer treatment can affect a women's sex life is by causing menopause earlier than normal. This is called premature menopause. Symptoms are often more severe than the slow changes that happen during a natural menopause. When a woman's ovaries are removed as part of a cancer surgery, or when the ovaries are affected by chemotherapy or radiation to the pelvis, the loss of estrogen can trigger hot flashes and vaginal atrophy (a condition when the vagina becomes tight and dry). Some women can take replacement hormones or use other methods to help these problems. Women with cancers of the breast or uterus usually cannot take estrogen, but they may benefit from some of the suggestions in the section, "Ways of dealing with sexual problems."

Women who have premature menopause sometimes have low androgen levels, which can lower sexual desire and pleasure. A blood test can find this problem. Often replacement androgen hormones can safely be prescribed.

If you are thinking of using hormones, it is wise to talk with your doctor or nurse to learn about the benefits and possible risks of hormonal therapy.

Orgasm

Women are usually able to have orgasms after cancer unless cancer or its treatment has damaged the spinal cord and caused the genital area to be numb. But even with spinal cord damage, there is early evidence that orgasm is possible, at least in some women.

Sometimes problems like pain during intercourse may distract a woman from reaching orgasm. In some cases, a woman might need to try different positions or types of genital touching. She might also need to practice having orgasms alone before going back to sex with a partner. (If you have had surgery for cancer in the pelvis or genital area, see the next section.)

Last Medical Review: 11/10/2008
Last Revised: 11/10/2008

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