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Hormone therapy, which is used to treat cancers of the breast
and of the lining of the uterus, starves the tumor of the hormone it
needs to grow.
This can be done using medicines. For example, the drug
tamoxifen keeps breast cancer cells from using estrogen. Other drugs --
exemestane, anastrozole, and letrozole -- keep testosterone from being
converted to estrogen.
A few women have their ovaries removed or have their ovaries
treated with radiation to make them inactive. This is another way to
deprive a cancer of the hormones it needs to grow.
Any of these treatments will most likely produce symptoms of
menopause. These include hot flashes, an interruption of the menstrual
cycle, and vaginal dryness. In spite of these changes, a woman should
still be able to feel sexual desire and reach orgasm. Sexual
intercourse will not cause harmful increases in estrogen levels in the
body.
When other hormone treatments no longer work, women with
breast cancer may also be treated with large doses of androgens (see "How
the female body works sexually"). This type of androgen
treatment may raise a woman's sexual desire. At the same time, large
doses of androgens can also deepen her voice, cause her to develop
acne, and cause the growth of facial hair. Her clitoris may also
enlarge slightly. But androgens will not change her personality or make
her feel more like a man. When androgens are given to control cancer,
the benefits usually outweigh the problems.
Very low doses of androgens may be used to treat women with
premature menopause. A small amount of androgen sometimes can boost
sexual desire without causing other side effects.
Last Medical Review: 11/10/2008
Last Revised: 11/10/2008
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