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Very little is known about the causes of lung carcinoid
tumors. Researchers have learned a lot about how certain risk factors
like cancer-causing chemicals or radiation can cause changes in lung
cells that lead to carcinomas, the more common type of lung cancer. But
these factors are not thought to play a large role in the development
of lung carcinoid tumors.
Carcinoid tumors probably develop from tiny clusters of
neuroendocrine cells in the lung airways called carcinoid tumorlets.
Tumorlets are sometimes found unexpectedly in lung biopsies done to
treat or diagnose other conditions. Under the microscope, tumorlets
resemble carcinoid tumors, except that they are much smaller -- less
than 5 mm (¼ inch) across.
Most tumorlets never grow any bigger, but some may eventually
become carcinoid tumors. Researchers still do not understand how
carcinoid tumorlets develop from lung neuroendocrine cells or why
tumorlets sometimes grow to become carcinoid tumors.
Last Medical Review: 03/09/2009 Last Revised: 03/09/2009
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