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As noted earlier, adult acute leukemia is not a single disease. It is really a group of
related diseases, and it is important to remember that patients with different subtypes of
acute leukemia vary in their prognosis and response to treatment. Treatment options for
each patient are based on the FAB subtype of the leukemia as well as certain prognostic
features. These prognostic features include the patient's age, white blood cell count,
cytogenetic test results, initial response to chemotherapy, and whether or not there was
an existing preleukemic condition (myelodysplastic syndrome), or another cancer treated
with chemotherapy, and/or without radiation therapy.
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