Non-Cancerous Breast Conditions

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Adenosis

Lobular carcinoma in situ

Lobular carcinoma in situ (lob-yuh-lur car-sin-O-ma in sy-too) or LCIS may also be called lobular neoplasia (nee-o-PLAY-zee-uh). In this breast change, cells that look like cancer cells are growing in the lobules of the milk-producing glands of the breast, but they do not grow through the wall of the lobules. LCIS is sometimes grouped with ductal carcinoma in situ (DCIS) as a non-invasive breast cancer, but it differs from DCIS in that it doesn’t become an invasive cancer if it isn’t treated.

Diagnosis

LCIS is diagnosed based on a biopsy (tissue is removed and checked under a microscope). Often, LCIS does not cause a tumor that can be felt or changes that can be seen on a mammogram. Most often, LCIS is found when a biopsy is done for another breast problem that is nearby. More information about pathology reports showing LCIS can be found in the document Understanding Your Pathology Report: Lobular Carcinoma In Situ.

Link to cancer risk

Women with LCIS have a 7 to 11 times higher risk of developing invasive cancer in either breast. For this reason, women with LCIS should make sure they have regular mammograms and doctor visits. Some women with LCIS choose to take medicine to lower their risk of breast cancer. More detailed information on this can be found in our document Medicines to Reduce Breast Cancer Risk.


Last Medical Review: 01/14/2014
Last Revised: 01/14/2014