American Cancer Society FluFOBT Program

The American Cancer Society FluFOBT program is intended to assist medical practices in increasing colorectal cancer (CRC) screening. It has been demonstrated in the medical literature that offering and providing take-home fecal occult blood tests (FOBTs) or fecal immunochemical tests (FITs) to patients at the time of their annual flu shot increases CRC screening rates. Successful Flu-FIT and Flu-FOBT Programs have been implemented in community health centers, in a public hospital, and in a large health maintenance organization. They have also been pilot tested in commercial pharmacies.

In this section, you will find information to develop and deliver a successful FluFOBT Program. For additional information and resources visit

American Cancer Society's FluFOBT Program: A Proven Approach to Increase Colorectal Cancer Screening

This presentation is designed for community health center clinical and support staff. It provides a brief overview of the science and rationale behind current colorectal cancer screening recommendations, information on the most common forms of testing, and an introduction to the ACS FluFOBT Program and its implementation in the community health center environment. Speaker notes (available here) contain additional information about slides in the presentation. 2015 version. 

ACS FluFOBT Implementation Guide

This guide includes background information about the FluFOBT Program and its benefits, as well as patient eligibility criteria and education materials. It lists the steps required to set up a FluFOBT training program in your health center, including staff training and tracking tools. 2015 version.

FOBT Clinicians’ Reference

Guidelines from the American Cancer Society, the US Preventive Services Taskforce, and others recommend high-sensitivity fecal occult blood tests (FOBT) as one option for colorectal cancer screening. This document provides state-of-the-science information about guaiac-based FOBT and fecal immunochemical tests (FIT).

FluFOBT - FluFIT Program Promotional Poster Thumbnail

Advertising Your FluFOBT or FluFIT Program

This print-ready, bilingual (English and Spanish) color poster can be used to promote both the importance of regular colorectal cancer screening and your upcoming FluFOBT or FluFIT program.


The American Cancer Society would like to thank Michael Potter, MD, former National Colorectal Cancer Roundtable (NCCRT) Steering Committee member and current chair of the NCCRT Professional Education and Practice Task Group, and his colleagues (at UCSF, the San Francisco Department of Public Health, and Kaiser Permanente) and funders (at ACS, CDC, and NCI) for developing and demonstrating the effectiveness of FluFOBT interventions. We thank FluFOBT project coordinators La Phengrasamy, MPH, Vicky Gomez, MPH, and Tina Yu for developing and field-testing many of the program materials and procedures included in this Implementation Guide. We would also like to thank Holly Wolf, PhD, MSPH, NCCRT Steering Committee member and chair of the NCCRT Policy Action Task Group, and her team at the Colorado Colorectal Screening Program for organizing the website materials into a model implementation guide.