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Peer Review Committees

Grant applications are ranked on the basis of merit by one of several discipline-specific research grant program Peer Review Committees. Each Peer Review Committee is composed of 12-25 scientific advisors, or peers, who are experts in their fields. The Council for Extramural Grants, a committee of senior scientists, recommends funding based on the relative merit of the applications, the amount of available funds, and the Society's objectives. Stakeholders, individuals with a personal interest in cancer, are full voting members of the Council and all Peer Review Committees. The stakeholders improved review by bringing a fresh appreciation of the dedication and impartiality of the volunteers who review the grants on scientific merit. No member of the American Cancer Society's Board of Directors or National Assembly may serve on a Peer Review Committee or as a voting member on the Council for Extramural Grants.

Molecular Genetics and Biochemistry of Cancer

This research grant program focuses on the genes involved in cancer and how alterations in those genes (mutations, deletions, and amplifications) play roles in the process. Also of interest is the examination of the molecules involved in cancer (proteins, nucleic acids, lipids, and carbohydrates) and how alterations in those molecules affect the disease. Molecular Genetics and Biochemistry of Cancer highlights potential targets for new treatments of cancer and mechanisms of signal transduction. This program is directed by Michael Melner, PhD.

Cancer Cell Biology and Metastasis

The primary goal of this grant program is to provide an understanding of the nature of cancer cells so they can be more effectively treated and eliminated. Emphases include understanding the fundamental controls of normal and cancer cells with a focus on how cells regulate when to grow, when to divide and when to die; how cells create an identity and how cells relate to the local environment and to other cells; how cells regulate when and how to move from one site to another. To most completely reach the program goal, a wide variety of cells are utilized so all aspects of cell biology can be examined. This program is directed by Charles (Karl) Saxe, PhD.

Preclinical and Translational Cancer Research

This research grant program focuses at the interface between laboratory investigations and human testing. The scope of the program includes investigations of the role of infectious diseases in cancer, the synthesis and discovery of cancer drugs, the creation and use of animal models of cancer, and the role of individual or groups of genes in different types of cancer. This program is directed by William Phelps, PhD.

Clinical Cancer Research and Immunology

This grant program focuses on increasing clinical research derived from advances in basic and epidemiologic research. Goals are to: pursue clinical trials of new imaging agents and modalities monitoring cancer development, progression and response to therapy; improve understanding of cancer-related inflammatory responses, immunosurveillance and immunotherapy; foster increased use of the immune system for cancer prevention; aid integration of immunotherapy into combination therapies for cancer; and increase fundamental knowledge of the effects of the environment and nutrition on cancer prevention, initiation and progression. This program is directed by William Chambers, PhD.

Cancer Control and Prevention Research

This research grant program focuses on the study of behaviors (of individuals or health care professionals or health care systems), or interventions in changing these behaviors or systems, resulting in either a reduction in cancer risk, enhancement in detecting it early, better informed treatment decision-making, or improvement in the quality of life of patients and families. Special emphasis is placed on reducing disparities in disadvantaged groups. This program is directed by Elvan Daniels, MD, MPH.

Health Professional Training in Cancer Control

This program provides grants in support of nurses, physicians and social workers to pursue training in outstanding programs that must meet high standards for excellence. The immediate goal is to encourage highly qualified individuals to enter careers in cancer prevention and control practice. The grant program goal is to accelerate the application of research findings in cancer prevention and control by increasing the number of nursing and social work clinicians and researchers with expertise in and career commitment to cancer control, and generalist physicians actively engaged in cancer control. This program is directed by Virginia Krawiec, MPA.

Peer Review Committee for Institutional Research Grants (IRG)

This committee reviews applications from institutions for block grants of seed money to support beginning investigators.This grant mechanism is directed by Virginia Krawiec, MPA.