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fluorescent in situ hybridization

[floo-res-uhnt in sy-too hi-brid-ih-ZAY-shun] also called FISH. A test that can help look at genes inside cells from a biopsy. It uses small deoxyribonucleic acid (DNA) probes labeled with special fluorescent dyes that only attach to certain parts of a gene to find specific DNA sequences. It can be used to diagnose, to evaluate prognosis (disease outlook), or to look at the remission of a disease. It is often used to count the number of HER2 genes in cancer cells. See also chromosome, cytogenetics, deoxyribonucleic acid, human epidermal growth factor receptor 2, remission.

How is multiple myeloma diagnosed?

... Fluorescent in situ hybridization. Fluorescent in situ hybridization (FISH)
is similar to cytogenetic testing. It uses special fluorescent ...

http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-diagnosis

Cancer Glossary

... FISH Search. see fluorescent in situ hybridization. ... fluorescent in situ
hybridization Search [floo-res-uhnt in sy-too hi-brid-ih-ZAY-shun]. ...

http://www.cancer.org/cancer/cancerglossary/index.aspx?letter=f

How is chronic myeloid leukemia diagnosed?

... Fluorescent in situ hybridization: Fluorescent in situ hybridization (FISH)
is another way to look at chromosomes. This test ...

http://www.cancer.org/cancer/leukemia-chronicmyeloidcml/detailedguide/leukemia-chronic-myeloid-myelogenous-diagnosis

How is breast cancer in men classified? | American Cancer ...

... FISH): This test uses fluorescent pieces of ... known as chromogenic in situ
hybridization (CISH), works ... color changes (not fluorescence) which may ...

http://www.cancer.org/cancer/breastcancerinmen/detailedguide/breast-cancer-in-men-classifying

How is breast cancer classified? | American Cancer Society

... FISH): This test uses fluorescent pieces of ... known as chromogenic in situ
hybridization (CISH), works ... for color changes (not fluorescence) and doesn ...

http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-classifying

FDA Approves New Test to Identify Herceptin Candidates

... are currently used to figure out if a patient's cancer is HER2-positive and will
likely respond to Herceptin: fluorescent in situ hybridization (FISH) and ...

http://www.cancer.org/cancer/news/news/fda-approves-new-test-to-identify-herceptin-candidates

Multiple Myeloma

... immunohistochemistry and flow cytometry, and chromosome analyses, including
karyotype and fluorescent in situ hybridization (also known as ...

http://www.cancer.org/acs/groups/cid/documents/webcontent/003121-pdf.pdf

References: Uterine sarcoma detailed guide

... P, Sklar J. Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR
and fluorescence in situ hybridization in endometrial stromal neoplasms. ...

http://www.cancer.org/cancer/uterinesarcoma/detailedguide/uterine-sarcoma-references

Special studies in cancer diagnosis

... Fluorescent in situ hybridization. Fluorescent in situ hybridization (FISH) is
a lot like cytogenetic testing. It can find most chromosome ...

http://www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies?ssdomainnum=5c38e88&ssdomainnum=5c38e88&ssdomainnum=5c38e88&url=http%3A//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%3Furl%3Dhttp%253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%253furl%253dhttp%25253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%25253furl%25253dhttp%2525253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%2525253furl%2525253dhttp%252525253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%252525253furl%252525253dhttp%25252525253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%25252525253furl%25252525253dhttp%2525252525253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%2525252525253furl%2525252525253dhttp%252525252525253a//www.cancer.org/treatment/understandingyourdiagnosis/examsandtestdescriptions/testingbiopsyandcytologyspecimensforcancer/testing-biopsy-and-cytology-specimens-for-cancer-special-studies%252525252525253fdocselected%252525252525253