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monoclonal antibodies

[ma-nuh-KLO-nuhl] man-made antibodies that are designed to lock onto certain antigens (substances that can be recognized by the immune system). Monoclonal antibodies have several uses in diagnosing and treating cancer. They are often used to help detect and classify cancer cells under a microscope. “Naked” monoclonal antibodies can attach to parts of cancer cells to either affect the cells directly or mark the cells so they can be found and attacked by the immune system. Other monoclonal antibodies are attached to chemotherapy drugs or radioactive substances and deliver these treatments directly to the cancer cells, killing them with little risk of harming healthy tissue. Research is still going on to learn more ways they can be used to find and treat cancer. See also antibody, antigen, chemotherapy, imaging tests, immunocytochemistry.

Monoclonal antibodies for chronic lymphocytic leukemia

... The monoclonal antibodies used to treat chronic lymphocytic leukemia (CLL)
can ... A number of monoclonal antibody drugs used to treat CLL target ...

http://www.cancer.org/cancer/leukemia-chroniclymphocyticcll/detailedguide/leukemia-chronic-lymphocytic-treating-monoclonal-antibodies

Monoclonal antibodies for Hodgkin disease

... Some monoclonal antibodies are now being used to treat Hodgkin disease.
Brentuximab vedotin (Adcetris™): This drug is an anti-CD30 antibody ...

http://www.cancer.org/cancer/hodgkindisease/detailedguide/hodgkin-disease-treating-monoclonal-antibodies

Monoclonal antibodies for chronic lymphocytic leukemia

... Monoclonal antibodies for chronic lymphocytic leukemia. ... The monoclonal
antibodies used to treat chronic lymphocytic leukemia (CLL) are: ...

http://www.cancer.org/cancer/leukemia-chroniclymphocyticcll/overviewguide/leukemia-cll-overview-treating-monoclonal-antibodies

Monoclonal antibodies to treat cancer

... They can then make many copies of that antibody in the lab. These are
known as monoclonal antibodies (mAbs or moAbs). ...

http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/immunotherapy/immunotherapy-monoclonal-antibodies

Other drugs for non-Hodgkin lymphoma in children

... Several monoclonal antibodies are now being used to treat lymphoma in ...
Rituximab (Rituxan): This antibody attaches to a substance called CD20 ...

http://www.cancer.org/cancer/non-hodgkinlymphomainchildren/detailedguide/non-hodgkin-lymphoma-in-children-treating-monoclonal-antibodies

What is multiple myeloma?

... normal plasma cells, so that antibodies to fight ... The antibody made by the
myeloma cells does ... copies of the same exact (or monoclonal) antibody. ...

http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-what-is-multiple-myeloma

What's new in Hodgkin disease research and treatment?

... Each antibody attacks only a specific target (usually a protein on the surface
of an unwanted cell). Monoclonal antibodies are man-made versions ...

http://www.cancer.org/cancer/hodgkindisease/detailedguide/hodgkin-disease-new-research

Cancer Immunotherapy

... They can then make many copies of that antibody in the lab. These are known
as monoclonal antibodies (mAbs or moAbs). Page 4. ...

http://www.cancer.org/acs/groups/cid/documents/webcontent/003013-pdf.pdf

Immunotherapy for non-Hodgkin lymphoma

... Several monoclonal antibodies are now being used to treat lymphoma.
Rituximab (Rituxan ® ): This is an antibody that attaches to a substance ...

http://www.cancer.org/cancer/non-hodgkinlymphoma/detailedguide/non-hodgkin-lymphoma-treating-immunotherapy

Types of cancer immunotherapy

... Next Topic. Monoclonal antibodies to treat cancer. ... They include: Monoclonal
antibodies: These are man-made versions of immune system proteins. ...

http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/immunotherapy/immunotherapy-types