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protein that normally causes damaged cells to die, which is very important to the body’s defenses against cancer. This protein is made by the TP53 tumor suppressor gene. See also TP53, tumor suppressor genes.

MediaRoom - Press Releases

... Dr. Levine is one of the key individuals credited with the discovery of the protein
p53 as a tumor suppressor, and his research has been cited as a ...


Do we know what causes rhabdomyosarcoma?

... For example, people with Li-Fraumeni syndrome have changes in the TP53
tumor suppressor gene that cause it to make a defective p53 protein. ...


Do we know what causes vulvar cancer?

... DNA tests from vulvar cancers in older women rarely show HPV infection, but
often show mutations of the p53 tumor suppressor gene. ...


What's new in oral cavity and oropharyngeal cancer research ...

... The protein produced by this gene (called p53) normally works to prevent cells
from growing too much and helps to destroy cells with too much ...


No Slide Title

... and associated with telomere dysfunction • Inhibiting p53 makes cancer cells
susceptible to ... Telomere dysfunction p53 accumulation ...


Do we know what causes adrenal cancer?

... cancers also. The Li-Fraumeni syndrome is caused by inherited mutations
that inactivate the p53 tumor suppressor gene. This ...


Electromagnetic Therapy

... treatment) use an electronic device they claim results in the self-destruction
of tumor cells by "energizing (or re-enlivening) the p53 gene." Some ...


Jones.NIH.Survivorship Plenary.Revised.pptx

... Effect of exercise on tumor growth as a funcTon of p53 status. Hursfing et al. ...
Med Sci Sports Exer, 2009 p53 (+/-‐ MMTV-‐Wnt-‐1 transgenic mice ...



... For example, people with Li-Fraumeni syndrome have changes in the TP53
tumor suppressor gene that cause it to make a defective p53 protein. ...


Lung Cancer

... the earliest genetic changes observed in the development of lung cancer;
other genes commonly mutated in lung cancer include p53, LKB1, and ...