Fertility and Men With Cancer

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Frequently asked questions

Should I have children after I’ve had cancer?

After a cancer diagnosis, many people wonder if they should even think about having children. They may question whether a genetic factor might have caused them to get cancer and if they might pass this cancer gene to their children. But only about 5% to 10% of cancers have a strong link to a gene that is passed on from parent to child. (See “Do children of cancer survivors have higher risks of getting cancer?” below.)

Survivors also may worry that treatment with chemo or radiation could cause birth defects or other health problems for future children. Many studies have found that babies conceived after cancer treatment don’t have birth defects or health problems any more often than babies whose parent didn’t have cancer. But problems are more likely if a baby is conceived during or too soon after cancer treatment, so it’s important to know how long to wait before trying to have a baby.

People with cancer already have many worries from dealing with the disease and its treatment. Concerns about the cancer coming back, how long they can expect to live now that they’ve had cancer, and the costs of raising a child are other serious issues that people with cancer face when thinking about having children.

There are no simple answers to the question of whether to have children. Each person’s cancer situation is unique. It helps to get as much information as you can before you make a decision that will affect the rest of your life as much as this one will. You might want to discuss these concerns with a genetic counselor, geneticist, reproductive specialist, and/or a mental health professional.

Depression, anxiety, and stress may affect your ability to think as clearly as you would like about your reproductive choices. Talk about these issues and concerns with the people whose opinions you value and trust – your spouse or partner, health care team, family, close friends, clergy, etc. There are support groups as well as health professionals who deal with fertility issues for people with cancer. Ask your doctor to refer you to one of these specialists.

If I didn’t act to preserve my fertility before cancer treatment, is it too late or do I still have options?

The answer to this question depends on your type of cancer and treatment. This is something you need to discuss with your oncologist. You may need to see a fertility specialist.

After cancer, how will I know if I need to see a fertility specialist?

It’s best to discuss fertility with your oncologist first, because everyone’s cancer diagnosis and treatment is different. But if you’ve had trouble conceiving for 6 to 12 months, despite having sex at the right times of the month, you may have a fertility problem and may need to see a specialist.

After cancer treatment, how long should I wait to conceive?

There is no set time. It’s very important to discuss this with your doctor to find out what’s best for you.

How long can sperm and tissues be frozen?

Indefinitely. Samples have been stored for decades without damage. Most of the risk occurs in the freezing and thawing processes, so once they are frozen they can be stored for many years.

What role does age play in fertility for men after cancer?

In general, a man’s fertility will begin to decline between ages 40 and 50. But cancer treatment can affect fertility in men of all ages, including boys who have not yet reached puberty.

Chemo may be more damaging to sperm production in men who are over 40.

Are the rates of birth defects higher in children born to cancer survivors who have had treatments like chemo and/or radiation therapy than in the general public?

So far studies strongly suggest that children born to cancer survivors are no more likely than others in the general public to have birth defects.

Do children of cancer survivors have higher risks of getting cancer?

Research shows that no unusual cancer risk has been identified in the offspring of cancer survivors. The exception to this is in families who have true genetic cancer syndromes. If there’s a lot of cancer in your family, you might want to check with a genetic counselor to see if any of your potential children would have a higher than usual chance of having cancer.

If it looks like I am fertile after treatment, should I use the sperm I froze before treatment?

Make this decision with the help of a fertility specialist or a reproductive endocrinologist. Most fertility specialists recommend that cancer survivors who recover fertility should try to conceive naturally with the sperm they are producing, but more research is needed in this area.

There’s no proof of an increased risk of birth defects in children born after cancer treatment. Fresh is usually preferred over frozen, but there could be other factors that affect your individual situation, so be sure to discuss this with a specialist.

Do cancer survivors have trouble adopting because of their medical history?

There’s no published research on this subject. Most adoption agencies say they do not rule out cancer survivors as parents. But they often require medical exams and a letter from an oncologist saying that the cancer survivor has a good prognosis (outlook for survival).

Some agencies or countries that offer international adoption may require a cancer survivor be cancer-free for 5 years before applying for adoption.

Some discrimination clearly does occur both in domestic and international adoption. Yet, most cancer survivors who want to adopt can do so. You may be able to find an agency that has experience working with cancer survivors.


Last Medical Review: 11/06/2013
Last Revised: 11/06/2013