- What is metastasis?
- What are the key statistics about bone metastases?
- What are the risk factors for bone metastases?
- Do we know why cancers metastasize to bones?
- Can bone metastases be prevented?
- Signs and symptoms of bone metastases
- How are bone metastases diagnosed?
- How are bone metastases treated?
- Systemic treatments for bone metastases
- Local treatments for bone metastases
- Pain medicines for bone metastases
- Clinical trials for bone metastases
- Complementary and alternative therapies for bone metastases
- Treating problems caused by bone metastases
- More treatment information about bone metastases
- What should you ask your doctor about bone metastases?
- Other things to consider
- Additional resources for bone metastases
- References: Bone Metastases
References: Bone Metastases
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Lipton A. Advances in treating metastatic bone cancer: Future treatment of bone metastases. Clin Cancer Res. 2006;12:6305s-6308s.
Lipton A, Steger GG, Figueroa J, et al. Extended efficacy and safety of denosumab in breast cancer patients with bone metastases not receiving prior bisphosphonate therapy. Clin Cancer Res. 2008;14:6690-6696.
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Patchell RA, Tibbs PA, Regine WF, et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: A randomised trial. Lancet. 2005;366:643-648.
Pavlakis N, Schmidt R, Stockler M. Bisphosphonates for breast cancer. Cochrane Database Syst Rev. 2005;(3):CD003474.
Ripamonti CI, Maniezzo M, Campa T, et al. Decreased occurrence of osteonecrosis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates. The experience of the National Cancer Institute of Milan. Ann Oncol. 2009;20:137-145.
Rosen LS, Gordon D, Kaminski M, et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial. Cancer. 2003;98:1735-1744.
Stopeck AT, Lipton A, Body JJ, et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study. J Clin Oncol. 2010;28:5132-5139.
Last Medical Review: 02/07/2014
Last Revised: 02/17/2014