Glossary Term:

Title

p53

Phonetic


Description

an important tumor suppressor gene that is not working properly in many cancers. The protein that this gene makes (also called p53) normally causes damaged cells to die. Mutations (changes) in this gene can be inherited (passed on from a parent) or they can happen during a person’s life. When these mutations are present, they can increase risk of many types of cancer. See also inherited disease, mutation, tumor suppressor genes.