Glossary Term:


reverse transcription polymerase chain reaction


re-<b>verse </b>tran-<b>scrip</b>-shun puh-<b>lim</b>-er-ace


also called RT-PCR. A very sensitive test for finding cancer-related genetic changes (mutations) in blood, bone marrow, lymph nodes, or other tissue. RT-PCR uses chemical analysis of the ribonucleic acid or RNA (a substance related to deoxyribonucleic acid or DNA) from genes affected by the translocation (in which DNA from one chromosome breaks off and gets attached to a different chromosome). See also bone marrow, chromosome, deoxyribonucleic acid, lymph node, mutation, ribonucleic acid, translocation.