Glossary Term:

Title

selective estrogen receptor modulator

Phonetic

SERM

Description

an estrogen-like substance that has some, but not all, of the actions of estrogen. For example, raloxifene is classified as a SERM because it (like estrogen) prevents bone loss and lowers serum cholesterol but unlike estrogen, does not stimulate the uterus to grow a lining. Tamoxifen and aromatase inhibitors are also SERMs. See also aromatase inhibitors, estrogen, uterus.