Chemotherapy, radiation therapy, surgery, stem cell or bone marrow transplant, steroids, or the cancer itself can suppress or weaken the immune system.
The usual doses of chemotherapy drugs can cause serious side effects in quickly dividing tissues such as the bone marrow (where new blood cells are made).
The signs and symptoms of neuroblastoma vary widely, depending on the size of the tumor, where it is, how far it has spread, and if the tumor cells secrete hormones.
Most people with Hodgkin disease see their doctor because they have felt a lump that hasn't gone away, they develop some of the other symptoms listed below, or they just don't feel well and go in for a checkup.