After Small Intestine Cancer Treatment

For some people with small intestine cancer, treatment can remove or destroy the cancer. Completing treatment can be both stressful and exciting. You may be relieved to finish treatment but find it hard not to worry about cancer coming back (recurrence). This is a very common concern if you've had cancer.

For others, cancer may never go away completely. You might get regular treatments, such as chemotherapy, radiation therapy, or other therapies to try to keep the cancer in check and to help relieve symptoms. Learning to live with cancer that doesn't go away can be difficult and very stressful. It has its own type of uncertainty.

Follow-up care after small intestine cancer

Even after you’ve completed treatment, your doctors will still want to watch you closely. Talk to them about developing a survivorship care plan for you. This plan can guide your next steps after treatment, including follow-up appointments and ways to stay healthy.

What’s usually in a survivorship care plan

A survivorship care plan might include:

  • A suggested schedule for follow-up exams and tests
  • A timeline for other tests, such as screening for other cancers, or monitoring for long-term health effects from your cancer or its treatment
  • A list of possible late or long-term side effects, including what to watch for and when to contact your doctor
  • Diet and physical activity suggestions
  • Reminders to keep seeing your primary care provider (PCP) for regular health care and cancer screening tests

What to expect during follow-up visits

Whether you have completed treatment or are still being treated, your cancer care team will still want to watch you closely. It’s very important to go to all follow-up appointments, as small intestine cancer can sometimes come back after treatment.

During your follow-up visits, your doctor will ask about symptoms, examine you, and may order blood tests or imaging tests such as CT scans. Your visits will likely be at least once every few months at first. The time between visits might then be extended over time if there are no signs that the cancer has returned.

Your follow-up visits are a good time to ask questions and talk about any changes or problems you notice and concerns you have. Some treatment side effects might last a long time or might not even show up until years after you have finished treatment.

Questions to ask your care team

  • Do I need a special diet after treatment?
  • Are there any limits on what I can do?
  • What symptoms should I watch for?
  • What kind of exercise should I do now?
  • What type of follow-up will I need after treatment?
  • How often will I need to have follow-up exams and imaging tests?
  • Will I need any blood tests?
  • How will we know if the cancer has come back? What should I watch for?
  • What will my options be if the cancer comes back?

Staying prepared and organized

Even if you’ve completed treatment, it’s still important to be organized and stay on top of your health. Keeping your records and health insurance coverage in order makes it easier to manage follow-up care, future checkups, and any new concerns that may come up.

Keep your health insurance

It’s very important to keep health insurance as a small intestine cancer survivor. It can help cover the cost of follow-up visits, tests, and any care you may need in the future. No one wants to think about cancer coming back, but it’s best to be prepared.

Save your medical records

At some point, you may see a new doctor who doesn’t know your cancer history. Keep copies of your medical records so you can easily share the details of your diagnosis and treatment when needed.

Can I lower my risk of the cancer progressing or coming back?

If you have (or have had) small intestine cancer, you probably want to know if there are things you can do that might lower your risk of the cancer growing or coming back, such as exercising, eating a certain type of diet, or taking nutritional supplements. Unfortunately, it’s not yet clear if there are things you can do that will help.

Adopting healthy behaviors such as not smoking, eating well, getting regular physical activity, and staying at a healthy weight might help, but no one knows for sure. However, we do know that these types of changes can have positive effects on your health that can extend beyond your risk of small intestine cancer or other cancers.

About dietary supplements

So far, no dietary supplements (including vitamins, minerals, and herbal products) have been shown to clearly help lower the risk of small intestine cancer progressing or coming back. This doesn’t mean that no supplements will help, but it’s important to know that none have been proven to do so.

Dietary supplements are not regulated like medicines in the United States – they do not have to be proven effective (or even safe) before being sold, although there are limits on what they’re allowed to claim they can do. If you’re thinking about taking any type of nutritional supplement, talk to your health care team. They can help you decide which ones you can use safely while avoiding those that might be harmful.

If the cancer comes back

If cancer does recur, your treatment options will depend on the location of the cancer, what treatments you’ve had before, and your current health and preferences. For more information on how small intestine cancer is treated, see Treatment Choices for Small Intestine Cancer (Adenocarcinoma), Based on Tumor Spread.

For more general information on dealing with a recurrence, see Understanding Recurrence.

Can I still get another type of cancer?

Unfortunately, being treated for cancer doesn’t mean you can’t get a second cancer. People who have had small intestine cancer can still get the same types of cancer that other people get. In fact, they are at higher risk for certain types of cancer. For example, they have an increased risk of other digestive tract cancers, especially colorectal cancer.

Because of this, it’s important to do what you can to lower your cancer risk, such as not smoking, staying at a healthy weight, staying active, and eating a healthy diet. And be sure to talk to your doctor about which cancer screening tests are right for you.

Getting emotional support

Some amount of feeling depressed, anxious, or worried is normal when cancer is a part of your life. Some people are affected more than others. But everyone can benefit from help and support from other people, whether friends and family, religious groups, support groups, professional counselors, or others. To learn more about this, see Life After Cancer.

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Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

National Cancer Institute. Physician Data Query (PDQ). Gastrointestinal Stromal Tumors Treatment. 2023. Accessed at www.cancer.gov/types/small-intestine/patient/small-intestine-treatment-pdq on January 13, 2026.

Stolzenberg-Solomon RZ, Fraumeni JF, Wideroff L, Albanes D, Curtis, RE. New Malignancies Following Cancer of the Digestive Tract, Excluding Colorectal Cancer. In: Curtis RE, Freedman DM, Ron E, Ries LAG, Hacker DG, Edwards BK, Tucker MA, Fraumeni JF Jr. (eds). New Malignancies Among Cancer Survivors: SEER Cancer Registries, 1973-2000. National Cancer Institute. NIH Publ. No. 05-5302. Bethesda, MD, 2006. Accessed at http://seer.cancer.gov/archive/publications/mpmono/MPMonograph_complete.pdf on January 13, 2025.

Last Revised: February 9, 2026

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