DetermiNation Endurance Series

DetermiNation is the American Cancer Society’s event endurance program, spanning a variety of sports including cycling, running, hiking, yoga, and more. The collective efforts of the dedicated athletes who use their fortitude to help raise funds to take down cancer are nothing short of amazing.

When you join DetermiNation, you’re not just participating in an endurance event. You’re pushing yourself to help save lives from cancer. Just like hard work goes into your event training, the American Cancer Society gives it our all through things like breakthrough research, patient programs and services, and a free 24/7 cancer helpline. Together, we’ll tackle every course, rally every community, and stay absolutely relentless in the fight against cancer.


Find an Event Near You

Use the search field below to find events in your community.

Keep in touch with us

Connect Through Social

Join the DetermiNation Facebook group

Our DetermiNation community spans from coast to coast. Join the official ACS DetermiNation Facebook group to connect and share with like-minded endurance athletes dedicated to the fight against cancer and learn more about the latest events.

Follow DetermiNation on Facebook
Follow DetermiNation on Instagram

Connect through Email

Learn more! Sign up and stay updated on the newest opportunities available through the American Cancer Society DetermiNation Endurance Series.

Elite Fundraising Club

Raise $5,000 to join the DetermiNation Pacesetter Club. This fundraising club comes with exclusive member benefits, special gifts, and recognition opportunities.

DetermiNation Pacesetters

By raising $5,000, all 2022 DetermiNation Pacesetters will receive:

  • Incentives: choice of a special DetermiNation branded gift
  • National-level recognition as an elite fundraiser for the Pacesetter Club
  • Exclusive Pacesetter communications, including newsletters, special recognition, and opportunities to spotlight your fundraising/training tips at all endurance events

2021 Top 10 Running Pacesetters

 Event Name  Participant Name  Amount Raised
 Pittsburgh Marathon  Cathy O'Brien $41,530.00 
 New York City Marathon  Mark Duffy $23,325.37 
 Golden Gate Half Marathon  Kate Johnson $22,363.06 
 New York City Marathon  Joseph Flore $22,206.18 
 Bank of America Chicago Marathon  Meg Pond Louthan $20,978.07 
 Sole Burner 5K Chaseburg  Linda DeGarmo $20,730.00 
 Virgin Money London Marathon  Mark Speciale $18,141.98 
 New York City Marathon  Jim Maffezzoli $17,812.35 
 New York City Marathon  Jan Lennertz $17,558.41 
 Bank of America Chicago Marathon  Kristin McQueen $16,161.07 

2021 Top 10 Cycling Pacesetters

 Event Name  Participant Name  Amount Raised
 Philadelphia Bike-A-Thon  Robert Braverman $107,076.19 
 Cycle The South Hope Ride  Mike Lee $89,347.46 
 Pan Ohio Hope Ride  James Bond $31,210.06 
 Pan Ohio Hope Ride  Mark Taft $31,056.87 
 Philadelphia Bike-A-Thon  Emil Skobeloff $23,861.51 
 Pan Ohio Hope Ride  Jeffrey Malish $18,624.11 
 Philadelphia Bike-A-Thon  Harry Roth $16,820.39 
 Pan Ohio Hope Ride  Andy Jones $16,800.83 
 Philadelphia Bike-A-Thon  Perry Benson $16,770.38 
 MA Bicycles Battling Cancer  Louise Santosuosso $16,578.55 


Fighting cancer through DetermiNation is a team effort. Thanks to the support of our partners, the American Cancer Society is able to produce athletic endurance events all over the country that help people reach their personal performance goals while bringing us closer to a world without cancer.

Ways to Participate

If you’d like to experience for yourself what DetermiNation can do, or even just show your support to someone else, we have you covered.