Apply for a Grant

As the nation's largest private, not-for-profit source of funds for scientists studying cancer, the American Cancer Society remains committed to funding basic, translational, clinical, and cancer control research now and in the future - as much as we are able given our available financial resources. 

NEWS About extramural grants

Grant Changes

Priority Areas for ACS Grant Applications

All research proposals must fall into at least 1 of these 6 priority areas: 

  1. Cause & Etiology
  2. Obesity & Healthy Eating & Active Living (HEAL)
  3. Screening & Diagnosis
  4. Treatment
  5. Survivorship
  6. Health Equity Across the Cancer Control Continuum

ACS Grant Mechanisms

How To Submit a Grant Application

Go to proposalCENTRAL to submit an electronic version by 11:59 pm ET on the specified deadline.* (We no longer require a paper copy, unless requested.)

Make sure to include contact information for  yourself, the institution official, technology transfer officer, and the department head.

See All Grant Policies and All Grant Instructions

Research grants for independent investigators

Discovery Boost Grants (DBG)

Also see Arizona Discovery Boost and AHEAD (Advancing Health Equity and Addressing Disparities) Awards

Who Can Apply: Independent investigators at any career stage.

Purpose: To fund exploratory research to develop research methodologies, establish feasibility, or pilot test high-risk/high-reward research across the research continuum.

UPDATED Funding: 2 years with $125K a year direct costs, plus 20% allowable indirect costs

Deadlines: April 1*  and Oct. 15* 

Mission Boost Grants

UPDATED—Who Can Apply: Current and past American Cancer Society grantees and now including former ACS Postdoctoral Fellows

Purpose: Enables transition of patient-focused research to accelerate clinical impact

Funding: Stage I: $240K over 2 years; Stage II: $600K for 1.5 years

Deadlines: April 1* and Oct. 15*

Research Scholar Grants (RSG)

Also see this special initiative PRIORITY FOCUS:
Health Equity Research in Cancer Control and Prevention

UPDATED—Who Can Apply: Investigators within the first 10 years of an initial independent research career or full-time faculty appointment

Funding: Up to 4 years with $165K a year direct costs, plus 20% allowable indirect costs

Deadlines: April 1* and Oct. 15*


Postdoctoral Fellowships (PF)

Increased Stipends and Expanded Eligibility!

Who Can Apply: Investigators who are a US citizen or a non-citizen holding an appropriate visa when the application is submitted and are within 4 years of receiving a doctoral degree 

Funding: Progressive stipends of $66K, $68K, and $70K for up to 3 years, plus an annual $4K fellowship allowance and $1,500 travel allowance in the final year

Application Deadlines:  April 1* and Oct. 15*

Clinician Scientist Development Grant (CSDG)


Who Can Apply: Licensed clinicians who are within the first 6 years of their initial, full-time faculty appointment and who have an active role in patient care.  

 3 to 5 years with $135K direct costs a year, plus 8% allowable indirect costs 

  April 1and Oct. 15*


Institutional Research Grants (IRG)

Who Can Apply: Awarded to institutions as block grants to provide seed money for newly independent investigators to initiate cancer research projects. The principal investigator of the grant should be a senior faculty member.

Funding: 1 to 3 years with an average of $120K a year, renewable

Deadline: April 1*


Requests for Applications
St. Baldrick's Foundation - American Cancer Society Childhood Cancer Research RFA: Pilot Accelerator Award 

Who Can Apply: Independent investigators at any career stage.

Purpose: To advance innovative translational pediatric cancer research conducted within the context of a clinical trial. 

Funding: 2 years with $100K a year direct costs, plus 20% allowable indirect costs

LOI Deadline: Dec. 5, 2022, at 10:59 PM EST

Full Application Deadline: April 1*

ACS Research Priority Area: Screening



Who Can Apply: Applicants for Interdisciplinary Team Award, Research Scholar Grant (any career stage), and Clinician Scientist Development Grant

Purpose: To fund innovative research that will facilitate more widespread cancer screening and early detection culminating in reduced cancer mortality.

Funding: Award length and budget varies by grant mechanisms

Application Deadline (all grant mechanisms): April 1*

Cancer Health Equity Research Centers (CHERCs)


Who Can Apply: Investigators at an accredited college, university, or medical school, within the United State (in accordance with ACS grant policies). Applicants from underrepresented groups and from Minority-Serving Institutions (MSIs) are encouraged to apply.

Funding: 4-year project with $4.08 M ($3.4 M direct cost plus 20% indirect cost)

Interactive Webinar about the Grant: February 21, 2023 at 1 PM ET

Resubmission Deadline: April 3, 2023

LOI Deadline: May 1, 2023

Application Deadline: October 16, 2023

Real-World Data Impact
Award (RWIA)

An American Cancer Society and
Flatiron Health, Inc. Collaboration

Who Can Apply: American Cancer Society (ACS) current and former grantees conducting health services, health policy research, or public heal data using real-world data. (Eligible applicants are specifically invited.)

Purpose: Use real-world data to accelerate cancer research on health equity that has a strong potential to inform public health, public policy, or to improve clinical practice and contribute to health equity

Funding: 1 year with $75,000 direct costs, no indirect costs allowed

LOI Required

Application Deadline (if invited): April 1*

The Role of Health Policy and
Health Insurance in Improving Access to and Performance of Cancer Care


Who Can Apply: Independent investigators at any career stage with a doctoral degree and a full-time faculty appointment or equivalent, who are evaluating changes in the health care system with a focus on cancer

Award length and budget varies

April 1and Oct. 15*

Research Professor Grants (RP)

Also see: ACS-Wilmott Family Professorship in Pancreatic Cancer

Who Can Apply: Investigators who are full professors and made seminal contributions that have changed the direction of cancer care research and who expect to continue to provide leadership in their research area

Funding: 5-year term with $80K a year; renewable

Letter of Intent (LOI) Deadline: Feb. 1
Application Deadline: April 1*

Clinical Research Professor Grants (CRP)

Who Can Apply: Investigators who are a full professor and made seminal contributions that have changed the direction of  clinical, psychosocial, behavioral, health policy, or epidemiologic cancer research and who expect to continue to provide leadership in their research area

 5-year term with $80K a year; renewable

Letter of Intent (LOI) Deadline:
 Aug. 1*

Application Deadline: Oct. 15*

* If the grant application deadline falls on a weekend or holiday, applications will be accepted the following business day.