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After Treatment for Mesothelioma
For some people with mesothelioma, treatment may remove or destroy the cancer. You may be relieved to finish treatment but find it hard not to worry about cancer coming back (recurrence). This is very common if you’ve had cancer.
For other people, mesothelioma may never go away completely. Some people may get regular treatments to try to keep the cancer in check for as long as possible. Learning to live with cancer that does not go away can be difficult, but many people find ways to manage their health and maintain a good quality of life.
Follow-up care
Talk with your doctor about developing a survivorship care plan for you. This plan can guide your next steps after treatment, including follow-up appointments and ways to stay healthy.
What’s usually in a survivorship care plan
A survivorship care plan might include:
- A suggested schedule for follow-up exams and tests
- A timeline for other tests, such as screening for other cancers, or monitoring for long-term health effects from your cancer or its treatment
- A list of possible late or long-term side effects, including what to watch for and when you should contact your doctor
- Diet and physical activity suggestions
- Reminders to keep seeing your primary care provider (PCP) for regular health care and cancer screening tests.
Typical follow-up schedule
There's no widely agreed upon follow-up schedule for people with mesothelioma. Your doctor will most likely want to see you at least every few months or so at first. The time between visits might get longer if there are no problems.
During these visits, your doctors will ask about symptoms, examine you, and might order blood tests or imaging tests, such as CT scans or PET scans.
Managing side effects
Even if you have completed treatment, your doctors will still want to watch you closely. Follow-up is needed to check for signs of cancer recurrence or spread, as well as possible side effects of certain treatments. It’s very important to go to all your follow-up appointments.
Almost any cancer treatment can have side effects. Some can last for weeks or months, but others can be permanent. Your doctor visits are a good time to ask questions and talk about any changes or problems you notice or concerns you have.
Questions to ask your care team
- Are there any limits on what I can do?
- Should I follow a specific diet or activity plan?
- What symptoms should I watch for?
- What type of follow-up will I need after treatment? How often will I need follow-up exams, blood tests, or imaging tests?
- How will we know if the cancer has come back?
- What will my options be if the cancer comes back?
Staying prepared and organized
Even if you’ve completed treatment, it’s still important to be organized and stay on top of your health. Keeping your records and health insurance coverage in order makes it easier to manage follow-up care, future checkups, and any new concerns that might come up.
Keep your health insurance
It’s very important to keep health insurance as a mesothelioma survivor. It can help cover the cost of follow-up visits, tests, and any care you might need in the future. No one wants to think about cancer coming back, but it’s best to be prepared.
Save your medical records
At some point, you might see a new doctor who doesn’t know your cancer history. Keep copies of (or have access to) your medical records so you can easily share the details of your diagnosis and treatment when needed.
Can I lower my risk of mesothelioma progressing or coming back?
If you have or have had mesothelioma, you probably want to know if there are things you can do that might lower your risk that it will or come back, such as exercising, eating a certain type of diet, or taking nutritional supplements. Unfortunately, it’s not yet clear if there are things you can do that will help.
Adopting healthy behaviors such as not smoking, eating well, getting regular physical activity, and staying at a healthy weight might help, but no one knows for sure. Still, we do know that these types of changes can have positive effects on your health that can extend beyond your risk of mesothelioma or other cancers.
About dietary supplements
So far, no dietary supplements, including vitamins, minerals, and herbal products, have been shown to clearly help lower the risk of mesothelioma progressing or coming back. This doesn’t mean that no supplements will help, but it’s important to know that none have been proven to do so.
Dietary supplements are not regulated like medicines in the United States. They do not have to be proven effective or safe before being sold, although there are limits on what they’re allowed to claim they can do.
If you’re thinking about taking any type of nutritional supplement, talk to your health care team. They can help you decide which ones you can use safely while avoiding those that might be harmful.
If the cancer comes back
If mesothelioma does come back at some point, your treatment options will depend on where the cancer is located, what treatments you’ve had before, and your health. To get an idea of how recurrent mesothelioma might be treated, see Treatment of Mesothelioma.
For more general information on recurrence, see Understanding Recurrence.
Getting emotional support
Some amount of feeling depressed, anxious, or worried is normal when cancer is a part of your life.
Some people are affected more than others. But everyone can benefit from help and support from other people, whether friends and family, religious groups, support groups, professional counselors, or others. Learn more in Life After Cancer.
- Written by
- References
Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).
Alexander HR, Kindler HL, Nowak AK. Peritoneal mesothelioma: Treatment. UpToDate. 2025. Accessed at https://www.uptodate.com/contents/peritoneal-mesothelioma-treatment on November 24, 2025.
Kindler HL, Ismaila N, Bazhenova L, et al. Treatment of Pleural Mesothelioma: ASCO Guideline Update. J Clin Oncol. 2025 Mar 10;43(8):1006-1038.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): Mesothelioma: Peritoneal. Version 2.2026. Accessed at www.nccn.org on November 24, 2025.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): Mesothelioma: Pleural. Version 2.2026. Accessed at www.nccn.org on November 24, 2025.
Pass HI, Tsao AS, Rosenzweig K. Initial management of malignant pleural mesothelioma. UpToDate. 2025. Accessed at https://www.uptodate.com/contents/initial-management-of-malignant-pleural-mesothelioma on November 24, 2025.
Tsao AS. Systemic treatment for unresectable malignant pleural mesothelioma. UpToDate. 2025. Accessed at https://www.uptodate.com/contents/systemic-treatment-for-unresectable-malignant-pleural-mesothelioma on November 24, 2025.
Last Revised: February 3, 2026
American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.
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