Surgery is rarely used to treat chronic myelomonocytic leukemia (CMML). Sometimes, though, surgery to remove the spleen may be an option if the patient is having problems from an enlarged spleen. Like all surgery, this has risks related to anesthesia and wound infection. Also, since the spleen helps protect against infection, removing it can increase the risk of severe infections. If you are considering having your spleen removed, discuss the risks and benefits with your doctor.
General information about surgery in the treatment of cancer can be found in Cancer Surgery.