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Signs and Symptoms of Uterine Sarcomas
Most uterine sarcomas are found because of symptoms they cause, such as abnormal vaginal bleeding. These symptoms can be caused by something else, such as noncancerous fibroids, hormone imbalance, precancer overgrowth of the endometrium (endometrial hyperplasia), or endometrial carcinoma.
If you have symptoms, see a doctor as soon as possible to find the cause and get treatment if needed.
Abnormal vaginal bleeding or spotting
Most people diagnosed with uterine sarcomas have abnormal vaginal bleeding. This includes:
- Bleeding between periods
- More bleeding during periods
- Bleeding after menopause
This is usually caused by conditions other than cancer, but it's important to have any abnormal bleeding checked right away.
Abdominal problems
Some people might experience swelling or a mass (lump) that can be felt in their belly, or they might have a general feeling of heaviness, fullness, or pain.
Vaginal discharge
Some people with uterine sarcomas have odorous vaginal discharge, with or without blood. Discharge is usually a sign of infection or another noncancerous condition, but it also can be a sign of cancer. Any abnormal discharge should be checked by a healthcare provider.
Urine or bowel problems
A mass in the uterus might push on the bladder, which can cause someone to urinate (pee) more often than usual. In some cases, a mass might block urine from passing out of the body or make it more difficult to have a bowel movement (constipation).
If cancer is advanced and has invaded nearby tissues, it might cause blood in the urine or stool.
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- References
Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).
Boggess JF, Kilgore JE, Tran AQ. Chapter 85: Uterine Cancer. In: Niederhuber JE, Armitage JO, Dorshow JH, Kastan MB, Tepper JE, eds. Abeloff’s Clinical Oncology. 6th ed. Philadelphia, Pa. Elsevier: 2020
Gaillard S, Secord A. Endometrial stromal sarcomas, related tumors, and uterine adenosarcoma. UpToDate. 2026. Accessed at https://www.uptodate.com/contents/endometrial-stromal-sarcomas-related-tumors-and-uterine-adenosarcoma on February 17, 2026.
Memarzadeh S, Berek J. Uterine sarcoma: Classification, epidemiology, clinical manifestations, and diagnosis. UpToDate. 2026. Accessed at https://www.uptodate.com/contents/uterine-sarcoma-classification-epidemiology-clinical-manifestations-and-diagnosis on February 17, 2026.
Last Revised: June 9, 2026
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