Key Statistics for Acute Lymphocytic Leukemia (ALL)

The American Cancer Society’s estimates for acute lymphocytic leukemia (ALL) in the United States for 2025 (including both children and adults) are:

• About 6,100 new cases of ALL (3,450 in males and 2,650 in females)
• About 1,400 deaths from ALL (720 in males and 680 in females)

The risk for developing ALL is highest in children younger than 5 years of age. The risk then declines slowly until the mid-20s, and begins to rise again slowly after age 50. Overall, about 4 of every 10 cases of ALL are in adults.

ALL is not a common cancer, accounting for less than half of 1% of all cancers in the United States. The average person’s lifetime risk of getting ALL is about 1 in 1,000. The risk is slightly higher in males than in females, and higher in White people than in Black or African American people.

Most cases of ALL occur in children, but most deaths from ALL (about 4 out of 5) occur in adults. Children may do better than adults because of differences in the nature of childhood and adult ALL, differences in treatment (children’s bodies can often handle aggressive treatment better than adult’s), or some combination of these.

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.