We are a diverse team that administers and manages data collection for the Population Science cohort studies, Cancer Prevention Study-II (CPS-II) and Cancer Prevention Study-3 (CPS-3). We also conduct statistical analyses and provide analytic support to other teams within the American Cancer Society (ACS).
The Study and Biospecimen team includes about a dozen people who manage the collection and storage of biospecimens for the American Cancer Society Cancer Prevention Studies (CPS). Around a half dozen data analysts make up the Analyst Core, which collect and evaluate the data that's used by epidemiology staff and others in the ACS Population Science department in their research studies.
We administer and manage the collection of data for CPS-II, and CPS-3 and carefully coordinate each step of the study process. For instance, we:
We receive data primarily from Population Science research studies and analyzes it by using a broad range of statistical methods.
We work with Population Science and other ACS researchers to incorporate our analyses into their studies. We also prepare CPS data for, and manage, collaborations and data-sharing agreements with external researchers in order to expand our ability to conduct impactful research.
A facility that collects, catalogs, and stores samples of biological materials (biospecimens). The ACS Cancer Prevention Studies biorepository includes blood, urine, buccal cells (from the inside of the cheek), cancer tissue, and stool.
The Study and Biospecimen team and Analyst Core provides support to many Population Science data collection and research initiatives, including our cancer prevention studies.
The Cancer Prevention Study-3 (CPS-3) is a large, geographically and racially/ethnically diverse US cohort of over 300,000 participants who provided blood samples and were cancer free at the time of enrollment (2006 to 2013).
The study was designed to collect information about the risk factors of cancer and about death from cancer in a cohort that reflects today’s society.
The Study and Biospecimen Management team:
The Analyst Core:
The Cancer Prevention Study-II (CPS-II) consists of 1.2 million men and women from across US who were enrolled starting in 1982.
In 1992, a sub-cohort called the CPS-II Nutrition Cohort was created with the goal of collecting updated and more detailed information on diet and other risk factors for cancer, as well as to be able to study the risk of developing cancer and dying from it.
From this cohort, another sub-set of participants, known as the Lifelink cohort, provided blood and buccal (cheek swab) samples to allow researchers to investigate the effects of genetics on cancer risk, development, and survival.
Over the course of this study, the Study and Biospecimen team:
Over the years, the Analyst Core has worked closely with ACS principal investigators to analyze CPS-II data resulting in an abundant amount of published research which explores a variety of cancer risk factors. Some of their most notable findings include: