Survival Rates for Childhood Leukemias

When discussing cancer survival statistics, doctors often use a number called the 5-year survival rate. This refers to the percentage of patients who live at least 5 years after their cancer is diagnosed. With acute leukemias, children who are free of the disease after 5 years are very likely to have been cured, because it’s very rare for these cancers to return after this long.

Survival rates are often based on previous outcomes of large numbers of children who had the disease, but they can’t predict what will happen in any child’s case. Knowing the type of leukemia is important in estimating a child’s outlook. But a number of other factors, including the child’s age and leukemia characteristics, can also affect outlook. Many of these factors are discussed in  Prognostic Factors In Childhood Leukemia (ALL or AML). Even when taking these other factors into account, survival rates are at best rough estimates. Your child’s doctor is likely to be a good source as to whether these numbers apply to your child, as he or she knows your situation best.

Current 5-year survival rates are based on children first diagnosed and treated more than 5 years ago. Improvements in treatment since then might result in a better outlook for children now being diagnosed.

Acute lymphocytic leukemia (ALL)

The 5-year survival rate for children with ALL has greatly increased over time and is now more than 85% overall.

Acute myelogenous leukemia (AML)

The overall 5-year survival rate for children with AML has also increased over time, and is now in the range of 60% to 70%. However, survival rates vary depending on the subtype of AML and other factors. For example, most studies suggest that the cure rate for acute promyelocytic leukemia (APL), a subtype of AML, is now higher than 80%, but rates are lower for some other subtypes of AML.

Other childhood leukemias

Accurate survival rates for less common forms of childhood leukemia are harder to find.

Juvenile myelomonocytic leukemia (JMML): For JMML, 5-year survival rates of about 50% have been reported.

Chronic leukemias: For chronic leukemias, which are rare in children, 5-year survival rates are less helpful, because some children may live for a long time with the leukemia without actually being cured. In the past, 5-year survival rates for chronic myelogenous leukemia (CML) were reported to be in the range of 60% to 80%. With newer, more effective medicines developed for CML in recent years, survival rates are likely to be higher now, although these new drugs have not been in use long enough to be sure.

The American Cancer Society medical and editorial content team
Our team is made up of doctors and master's-prepared nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.

Last Medical Review: April 17, 2015 Last Revised: February 3, 2016

American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.