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Key Statistics for Childhood Leukemia

Leukemia is the most common cancer in children and teens. Overall, however, childhood leukemia is a rare disease.

Acute leukemias

About 3 in 4 leukemias among children and teens are acute lymphoblastic leukemia (ALL). Most of the remaining cases are acute myeloid leukemia (AML).

  • ALL is most common in early childhood, peaking between ages 2 and 5 years.
  • ALL is slightly more common among Hispanic and White children than among African American and Asian American children, and it is more common in boys than in girls.
  • AML is much more common in adults than children. When it occurs in childhood, it is more likely in the first year of life and the teenage years.
  • AML occurs about equally among boys and girls of all races.

Chronic leukemias

Chronic leukemias are rare in children. Most of these are chronic myeloid leukemia (CML), which tends to occur more in teens than in younger children.

Juvenile myelomonocytic leukemia (JMML)

Juvenile myelomonocytic leukemia (JMML) is rare. It usually occurs in younger children, with an average age of about 2 years. It is more common in boys than in girls.

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.

For statistics related to survival, see Survival Rates for Childhood Leukemias.

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Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

American Cancer Society. Cancer Facts & Figures 2025. Atlanta, GA: American Cancer Society; 2025.

Aplenc R, Elgarten CW, Choi JK, Meshinchi S. Chapter 17A: Acute Myeloid Leukemia and Myelodysplastic Syndromes. In: Blaney SM, Adamson PC, Helman LJ, eds. Pizzo and Poplack’s Pediatric Oncology. 8th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2021.

Gramatges MM, O’Brien MM, Rabin KR. Chapter 16: Acute Lymphoblastic Leukemia. In: Blaney SM, Adamson PC, Helman LJ, eds. Pizzo and Poplack’s Pediatric Oncology. 8th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2021.

Puumala SE, Ross JA, Aplenc R, Spector LG. Epidemiology of childhood acute myeloid leukemia. Pediatr Blood Cancer. 2013;60(5):728-733. doi:10.1002/pbc.24464

Rau RE, Loh ML. Chapter 17B: Myeloproliferative Neoplasms of Childhood. In: Blaney SM, Adamson PC, Helman LJ, eds. Pizzo and Poplack’s Pediatric Oncology. 8th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2021.

Last Revised: July 22, 2025

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