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Key Statistics About Kaposi Sarcoma
Kaposi sarcoma (KS) is an uncommon cancer in the United States. It is much more common in some other parts of the world, such as Sub-Saharan Africa.
There are about 3 to 4 cases of KS per million people each year in the US.
During the peak of the AIDS epidemic, the number of cases of KS in the US rose sharply. With antiretroviral therapy (ART) for HIV and AIDS, HIV-related KS has become less common. Still, it is much more frequent in people living with HIV, with about 470 cases per million people each year.
All types of KS are more common in men than in women. The reasons for this aren’t fully understood.
KS is rare in children in the US, although it is more common in Sub-Saharan Africa, where infection with Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8), is widespread.
People who’ve had an organ transplant have about 200 times higher risk of KS compared to other people in the US. This is mainly because of the medicines needed to suppress the immune system after transplant.
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- References
Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).
Balasubramanian D, Srinivasan S, Paul PM, Ko N, Garlapati S. A retrospective study on the incidence of Kaposi sarcoma in the United States from 1999 to 2020 using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research (CDC WONDER) database. Cureus. 2025 Jan 10;17(1):e77213.
Bettuzzi T, Lebbe C, Grolleau C. Modern approach to manage patients with Kaposi sarcoma. J Med Virol. 2025 Mar;97(3):e70294.
National Cancer Institute. Kaposi Sarcoma Treatment (PDQ®)–Health Professional Version. 2025. Accessed at https://www.cancer.gov/types/soft-tissue-sarcoma/hp/kaposi-treatment-pdq on September 25, 2025.
Peprah S, Engels EA, Horner MJ, et al. Kaposi sarcoma incidence, burden, and prevalence in United States people with HIV, 2000-2015. Cancer Epidemiol Biomarkers Prev. 2021;30(9):1627-1633.
Last Revised: December 5, 2025
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