Key Statistics for Small Intestine Cancer

Although the small intestine makes up the largest part of the gastrointestinal (GI) tract, small intestine cancers are rare in the United States. In fact, they account for fewer than 1 in 10 cancers of the GI tract, and fewer than 1 in 100 cancers overall.

Small intestine cancer estimates for 2026

The American Cancer Society estimates for these cancers in the United States for 2026 are:

  • About 14,450 people will be diagnosed with some type of small intestine cancer.
  • About 2,170 people will die of small intestine cancer.

Who gets small intestine cancer?

Cancers of the small intestine tend to occur more often in older people. They are most often found in people in their 60s and 70s.

More key statistics

For statistics related to survival, see Survival Rates for Small Intestine Cancer (Adenocarcinoma).

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.

side by side logos for American Cancer Society and American Society of Clinical Oncology

Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

American Cancer Society. Cancer Facts & Figures 2026. Atlanta: American Cancer Society; 2026.

National Cancer Institute. SEER Cancer Stat Facts: Small Intestine Cancer. Accessed at http://seer.cancer.gov/statfacts/html/smint.html on Dec 10, 2025.

Last Revised: February 19, 2026

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