Our 24/7 cancer helpline provides support for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.
Chat live online
Select the Live Chat button at the bottom of the page
At our National Cancer Information Center trained Cancer Information Specialists can answer questions 24 hours a day, every day of the year to empower you with accurate, up-to-date information to help you make educated health decisions. We connect patients, caregivers, and family members with valuable services and resources.
Or ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
Referrals to patient-related programs or resources
Donations, website, or event-related assistance
Tobacco-related topics
Volunteer opportunities
Cancer Information
For medical questions, we encourage you to review our information with your doctor.
The exact cause of most vaginal cancers is not known. But scientists have found that it is linked to a number of conditions described in Risk Factors for Vaginal Cancer Research is being done to learn more about how these risk factors cause cells of the vagina to become cancer.
Research has shown that normal cells make substances called tumor suppressor geneproducts to keep from growing too rapidly and becoming cancers. High-risk HPV (human papillomavirus) types (like 16 and 18) produce 2 proteins (E6 and E7) that can change the way known tumor suppressor gene products work.
Women exposed to diethylstilbestrol (DES) as a fetus (that is, their mothers took DES during pregnancy) are at increased risk for developing clear cell carcinoma. DES also increases the likelihood of vaginal adenosis (gland-type cells in the vaginal lining rather than the usual squamous cells). Most women with vaginal adenosis never develop vaginal clear cell carcinoma. Still, those with a rare type of adenosis called atypical tuboendometrial adenosis do have a higher risk of developing this cancer.
Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.