Key Statistics for Vaginal Cancer

Learn about key statistics for vaginal cancer, including how common it is, who is most affected, and the outlook for those with a diagnosis.

How common is vaginal cancer?

Vaginal cancer is rare. It accounts for 1% to 2% of cancers in the female genital tract, and a very small portion of cancers overall. There are about 8,000 cases diagnosed each year. Vaginal cancer is more common among women in their 60s and older.

About 75% of vaginal cancers are caused by the human papillomavirus (HPV).

What is the outlook for people with vaginal cancer?

For survival statistics related to vaginal cancer, see Survival Rates for Vaginal Cancer.

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.

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Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

Adams TS, Maluleke JC, Cuello MA. Cancer of the vagina: 2025 update. Int J Gynaecol Obstet. 2025;171 Suppl 1(Suppl 1):48-59.

Alemany L, Saunier M, Tinoco L, et al. Large contribution of human papillomavirus in vaginal neoplastic lesions: a worldwide study in 597 samples. Eur J Cancer. 2014;50(16):2846-2854.

Kaltenecker B, Dunton CJ, Tikaria R. Vaginal Cancer. In: StatPearls. Treasure Island (FL): StatPearls Publishing; March 1, 2023.

Sinno AK, Saraiya M, Thompson TD, et al. Human papillomavirus genotype prevalence in invasive vaginal cancer from a registry-based population. Obstet Gynecol. 2014;123(4):817-821. 

Last Revised: October 23, 2026

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