Adenocarcinoma is a type of cancer that develops in gland cells. Squamous carcinoma of the esophagus is a type of cancer that starts in the squamous cells that line the esophagus. (The esophagus is the tube that connects the mouth to the stomach.)
A number of things, including chronic reflux (regurgitation) of the stomach contents up into the esophagus, trauma from taking medicines, and infections can injure the squamous lining of the esophagus. The esophagus reacts to the injury and tries to repair itself. This creates changes that can be seen under the microscope that are called reactive changes.
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