Can Cervical Cancer Be Prevented?

The two most important things you can do to prevent cervical cancer are to get the HPV vaccine if you are eligible, and to be tested according to American Cancer Society guidelines. These can be found in The American Cancer Society Guidelines for the Prevention and Early Detection of Cervical Cancer.

The most common form of cervical cancer starts with pre-cancerous changes and there are ways to stop this from developing. The first way is to find and treat pre-cancers before they become invasive cancers, and the second is to prevent the pre-cancers.

Finding cervical pre-cancers

A well-proven way to prevent cervical cancer is to have screening tests. Screening is having tests to find conditions that may lead to cancers and can find pre-cancers before they can turn into invasive cancer. The Pap test (or Pap smear) and the human papillomavirus (HPV) test are specific tests used during screening for cervical cancer. If a pre-cancer is found it can be treated, keeping it from turning into a cervical cancer.

The Pap test or smear is a procedure used to collect cells from the cervix so that they can be looked at closely in the lab to find cancer and pre-cancer. It's important to know that most invasive cervical cancers are found in women who have not had regular Pap tests. A Pap test can be done during a pelvic exam, but not all pelvic exams include a Pap test.

An HPV test can be done on the same sample of cells collected during the Pap test.  The HPV test checks if there is an HPV infection which is one condition that can lead to pre-cancers. 

Things to do to prevent pre-cancers and cancers

Based on your age, overall health, and personal risk for cervical cancer, there are some things that can be done that may prevent pre-cancers and conditions that lead to pre-cancers.

Get a HPV vaccine

Vaccines are available that can protect young people against certain HPV infections. These vaccines protect against infection with the HPV subtypes most commonly linked to cancer, as well as some types that can cause anal and genital warts.

These vaccines only work to prevent HPV infection − they will not treat an infection that is already there. That is why, to be most effective, the HPV vaccines should be given before a person becomes exposed to HPV (such as through sexual activity).

These vaccines help prevent pre-cancers and cancers of the cervix. Some HPV vaccines are also approved to help prevent other types of cancers and anal and genital warts.

The vaccines require a series of injections (shots). Side effects are usually mild. The most common one is short-term redness, swelling, and soreness at the injection site. Rarely, a young person might faint shortly after the injection.

The CDC recommends:

  • The HPV vaccination start at ages 11 or 12 years (or can be given early as age 9 years).
  • If not vaccinated already, everyone can get the vaccine through age 26 years. It’s important to know that vaccination at older ages is less effective in lowering cancer risk.
  • Vaccination is not recommended for everyone older than age 26 years. However, some adults age 27 through 45 years who are not already vaccinated may decide to get the HPV vaccine after speaking with their health care provider about their risk for new HPV infections and the possible benefits of vaccination. HPV vaccination in this age range provides less benefit. 

It’s important to know that no vaccine provides complete protection against all cancer-causing types of HPV, so routine cervical cancer screening is still needed.

For more information on the vaccine and HPV, please see HPV Vaccines.

Limit exposure to HPV

HPV is passed from one person to another during skin-to-skin contact with an infected area of the body. Although HPV can be spread during skin to skin contact − including vaginal, anal, and oral sex − sex doesn't have to occur for the infection to spread. All that is needed is skin-to-skin contact with an area of the body infected with HPV. This means that the virus can be spread without sex. It is even possible for a genital infection to spread through hand-to-genital contact.

Also, HPV infection seems to be able to spread from one part of the body to another. This means that an infection may start in the cervix and then spread to the vagina and vulva.

It can be very hard not to be exposed to HPV. It may be possible to prevent HPV infection by not allowing others to have contact with your anal or genital area, but even then there might be other ways to become infected that aren’t yet clear. 

Limiting the number of sex partners and avoiding sex with people who have had many other sex partners may lower your risk of exposure to HPV.  But again, HPV is very common, so having sexual activity with even one other person can put you at risk. Remember that someone can have HPV for years and still have no symptoms. So it's possible someone can have the virus and pass it on without knowing it.

Use a condom

Condoms (“rubbers”) provide some protection against HPV but they don’t completely prevent infection. One reason that condoms cannot protect completely is because they don’t cover every possible HPV-infected area of the body, such as skin of the genital or anal area. Still, condoms provide some protection against HPV, and they also help protect against HIV and some other sexually transmitted infections. 

Don't smoke

Not smoking is another important way to reduce the risk of cervical pre-cancer and cancer.

The American Cancer Society medical and editorial content team

Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.

Centers for Disease Control and Prevention (CDC). Evidence to Recommendations for HPV Vaccination of Adults, Ages 27 through 45 years: Updated HPV Vaccination Recommendations of the Advisory Committee on Immunization Practices. Accessed at on December 09, 2019. 

Centers for Disease Control and Prevention (CDC). Vaccinating Boys and Girls. Accessed at on January 08, 2020. 

Centers for Disease Control and Prevention (CDC). Use of 9-Valent Human Papillomavirus (HPV) Vaccine: Updated HPV Vaccination Recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2015 March 27;64(11):300−304.

National Cancer Institute. Physician Data Query (PDQ). Cervical Cancer Prevention – Patient Version. 2019. Updated March 8, 2019. Accessed on November 1, 2019.

Plummer M, Herrero R, Franceschi S, et al; IARC Multi-centre Cervical Cancer Study Group. Smoking and cervical cancer: Pooled analysis of the IARC multi-centric case-control study. Cancer Causes Control. 2003;14:805-814.

Roura E, Castellsagué, X, Pawlita M, et al. Smoking as a major risk factor for cervical cancer and pre-cancer: Results from the EPIC cohort. Int J Cancer. 2014; 135: 453–66.

Saslow D, Andrews KS, Manassaram-Baptiste D, et al. Human papillomavirus vaccination guideline update: American Cancer Society guideline endorsement. CA Cancer J Clin. 2016.

Saslow D, Solomon D, Lawson H, et al. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. CA Cancer J Clin. 2012;62:147-172.

Tokudome S, Suzuki S, Ichikawa H, et al. Condom use promotes regression of cervical intraepithelial neoplasia and clearance of human papillomavirus: a randomized clinical trial. Int J Cancer. 2004;112:164.

Warner K. Huh, Kevin A. Ault, David Chelmow, et al. Use of Primary High-Risk Human Papillomavirus Testing for Cervical Cancer Screening: Interim Clinical Guidance. J Lower Gen Tract Dis. 2015;19: 91–96.

Winer RL, Hughes JP, Feng Q, et al. Condom use and the risk of genital human papillomavirus infection in young women. N Engl J Med. 2006;354:2645-2654.

Zhu H, Shen Z, Luo H, Zhang W, Zhu X. Chlamydia Trachomatis Infection-Associated Risk of Cervical Cancer: A Meta-Analysis. Medicine (Baltimore). 2016;95(13):e3077. doi:10.1097/MD.0000000000003077.

Last Medical Review: January 3, 2020 Last Revised: January 3, 2020

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