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Key Statistics for Chronic Lymphocytic Leukemia (CLL)
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The American Cancer Society's estimates for chronic lymphocytic leukemia (CLL) in the United States for 2026 are:
- About 22,760 new cases of CLL (13,810 in men and 8,950 in women)
- About 4,350 deaths from CLL (2,720 in men and 1,630 in women)
CLL accounts for about 1 in 3 new cases of leukemia in the US, and about 1% of cancers overall.
CLL is slightly more common among men than women, but the average lifetime risk of getting CLL for both sexes is about ½ of 1%.
CLL mainly affects older adults. The average age of people when they are diagnosed is around 70 years. It's rarely seen in people under age 40, and it's extremely rare in children.
Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.
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- References
Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).
American Cancer Society. Cancer Facts & Figures 2026. Atlanta: American Cancer Society; 2026.
National Cancer Institute. Cancer Stat Facts: Leukemia-Chronic Lymphocytic Leukemia (CLL). 2024. Accessed at https://seer.cancer.gov/statfacts/html/clyl.html on January 30, 2025.
Last Revised: January 13, 2026
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