Most cases of uterine sarcoma cannot be prevented.
Although pelvic radiation increases the risk of developing a uterine sarcoma, the benefit of pelvic radiation in treating other cancers far outweighs the risk of developing a rare cancer such as uterine sarcoma many years later.
The risk of developing uterine sarcomas while taking tamoxifen is small and there are not specific things you can do to prevent a uterine sarcoma if you're taking it. But doctors will most likely watch you closely with regular pelvic exams and ask you to get medical care as soon as possible if you start to bleed abnormally from the uterus.
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Last Revised: September 20, 2022