Grant applications are ranked on the basis of merit by one of several discipline-specific research grant program Peer Review Committees. Each Peer Review Committee is composed of 12-25 scientific advisors, or peers, who are experts in their fields. The Council for Extramural Grants, a committee of senior scientists, recommends funding based on the relative merit of the applications, the amount of available funds, and the Society's objectives. Stakeholders, individuals with a personal interest in cancer, are full voting members of the Council and all Peer Review Committees. The stakeholders improve review by bringing a fresh appreciation of the dedication and impartiality of the volunteers who review the grants on scientific merit. No member of the American Cancer Society's Board of Directors may serve on a Peer Review Committee or as a voting member on the Council for Extramural Grants.