Mission Boost Grants (MBG)
Grant Overview
Mission Boost Grants (MBG) are designed to support research projects that specifically focus on translation to human testing. MBGs are opportunities for independent investigators at all levels to apply for additional, or "boost," resources for innovative, clinical-enabling projects.
MBGs offer 2 stages of funding:
- Stage I requires the investigator to develop outcome-specific, unequivocal milestones that reduce the risks of studying a new drug, device, or procedure in patients.
- Stage II supports testing in cancer patients.
Eligibility
Stage I Mission Boost
We no longer require MBG applicants to be current or former ACS grantees or fellows. Starting in 2025, you ARE eligible to submit a proposal if you:
- Work at an academic institution in the United States or eligible nonprofit
- Are an independent investigator with a full-time faculty appointment (or equivalent). Applicants may be at any career stage.
Stage II Mission Boost
You ARE eligible to submit a proposal if you:
- Work at an academic institution in the United States or eligible nonprofit
- Are an independent investigator with a full-time faculty appointment (or equivalent). Applicants may be at any career stage.
- Previously held or currently hold a Stage I Mission Boost Grant for a minimum of 18 months AND have completed Stage I milestones
Grant Term and Budget
Stage I Mission Boost
Stage I will be for a term of up to 2 years with an allowable budget of $135,000 per year direct costs plus 10% allowable indirect costs ($297,000 allowable total costs).
Stage II Mission Boost
Stage II will be for a term of up to 18 months with an allowable budget up to $545,000 direct costs plus 10% allowable indirect costs.
Application Deadlines
June 1, 2025 and December 1, 2025
If the grant application deadline falls on a weekend or holiday, applications will be accepted the following business day.
Want to see some recently published studies from grantees?
Go to Research Highlights.
