Juvenile myelomonocytic leukemia (JMML) is fairly rare, so it has been hard to study which treatment might be best. There is no clear single best chemotherapy treatment for this leukemia. A stem cell transplant is the treatment of choice when possible, as it offers the best chance to cure JMML. About half of the children with JMML who get a stem cell transplant are still free of leukemia after several years. Sometimes, even if the leukemia recurs, a second stem cell transplant can be helpful.
Because JMML is hard to treat with current chemo drugs, taking part in a clinical trial looking at newer drugs may be a good option for children who can’t get a stem cell transplant.
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Last Revised: February 12, 2019