RFA: Biology to Prevention Award (CRUK)
Purpose
The Biology to Prevention Awards aim to stimulate translational research that will build and use greater biological and mechanistic understanding of cancer aetiology, genesis, and risk, that will lead to precision prevention interventions.
Program Overview
Cancer Research UK (CRUK) has partnered with the American Cancer Society (ACS) to jointly consider primary prevention research applications in the scientific remit of the Biology to Prevention Award scheme to enable joint, collaborative applications with UK and US-based researchers.
Mark Your Calendar
ACS Budget Submission: June 13, 2025
Application Deadline: June 19, 2025
Submission Review: November
Award Funding Begins: January 2026
We welcome clear, well-defined, and discrete joint applications from UK- and US-based research teams, each based at the respective eligible host institution. Applications are expected to represent a true scientific partnership, involving meaningful collaboration with equal, intellectual partnerships, when possible, between the UK and US lead applicants. Each primary investigator should bring complementary, yet distinct, expertise to enable a multidisciplinary approach to address a critical research question.
Applications must include a description of the rationale and nature of the proposed collaboration, the specific role of all investigators, and synergistic opportunities.
Evidence of prior productive collaborations between members of the team is helpful. New teams should provide evidence of synergy among disciplines and areas of translational research that will foster innovation.
Eligibility
Applicants may be at any career stage.
At least 1 applicant must be an independent investigator with a full-time faculty appointment (or equivalent), at an eligible US institution, and at least 1 applicant must have the same qualifications at an eligible UK institution.
Grant Budget and Term
Through this cost-share partnership, CRUK will cover the admissible UK research costs (up to £600,000) and the ACS will cover the US-based research costs (up to $860,000 plus 10% indirect costs for a total of up to $946,000).
Awards can be up to 5 years in duration but must be at least 1 year.
Application and Review Process
- The UK-based lead applicant must contact the CRUK office with a brief outline of the proposed
research to set up an informal and confidential discussion and to confirm the proposal is in remit.
Once confirmed, the CRUK office will provide UK applicants with a private link to commence an
application on Flexi-Grant.
- The US-based lead applicant must submit the US PI's budget in ProposalCentral. The ACS program office will review the budget to confirm admissible costs (including indirect costs) in accordance with ACS funding policies. The ACS must approve the budget before the co-PIs can submit a full application to CRUK.
- UK-based applicants complete all required sections of the applications and are responsible for submitting it by the CRUK submission deadline. To be considered eligible for funding, applications must include a complete ACS budget.
Webinar Information
Listen to this recording of a recent webinar to learn more about this new co-funding opportunity.
ACS Program Contact: Paul Campbell, PhD, at paul.campbell@cancer.org
CRUK Program Contact: pprc@cancer.org.uk
